Lichen simplex chronicus des Analbereiches und seine Differenzialdiagnosen

Abstract

Lichen simplex chronicus (LSC) of the anal region is characterized by massive pruritus, constant itching and a chronic course. Histology is notable for a pseudoepitheliomatous hyperplasia. Correct diagnosis as well as therapy of anal LSC sometimes is difficult. Differential diagnostic considerations include verrucous lichen planus and squamous cell carcinoma. We present three cases and then summarize pathogenesis, diagnostics, differential diagnoses and therapeutic options for lichen simplex chronicus of the anal region.

Fluorescence diagnostics as a guide for demarcation and biopsy of suspected anal cancer

“…We have presented two patients who were referred to our clinic suffering from ostensibly similar problems in the anal region but in whom the final diagnoses, prognoses, and subsequent therapies were very different. The differential diagnosis of anal carcinoma includes many benign and malignant lesions 16 …”

Scrotal Swellings Synopsis of Differential Diagnosis (Part III)

“…Lichen simplex chronicus (LSC) [9,24] Lichen amyloidosis [10,25,26] Intense, intermittent pruritus, scrotal erythema and edema Erectile dysfunction(ED) [27] Stable pruritic plaque(s), marked by thickening, pigmentation exaggerated skin markings, the lichenification complemented by histopathology.…”

“…Scrotum being one of the pre-eminent parts. The scrotal swellings [3][4][5] are menacing challenging proposition affecting any of its structures starting with affliction of the skin in the form of angioderma [6] ; acquired angioderma(AAE) [7] and hereditary angioderma (HAE) [8] and lichen simplex chronicus (LSC) [9] . Besides, inflammation of the testis, the orchitis [10,11] , epididymis, the epididimitis [11][12][13] , and /or epididmo-orchitis [14,15] , pampiniform plexus, the Vericocele [16] , testicular torsion [17] , and collection of fluid in the tunica vaginalis testis, the Hydrocele [18] and exit/ slipping of small bowel into the scrotum, the inguinal hernia are its other presentations.…”

Erythema and erosions of the perianal region in a 49‐year‐old man

“…Beim Lichen ruber der Mundschleimhaut, insbesondere bei immunsupprimierten Patienten, wird in der Literatur die Gefahr einer malignen Entartung in bis 5 % der Fälle angegeben [9]. Dies ist auch beim analen Lichen ruber anzunehmen bei allerdings sehr dürftiger Datenlage [8].…”