Lichen simplex chronicus (atopic/neurodermatitis) of the anogenital region

Abstract

Lichen simplex chronicus (LSC) of the anogenital area is an eczematous disease characterized by unremitting itching and scratching. In most instances, it arises in individuals who are genetically atopic, and as such, LSC can be viewed as a localized variant of atopic/neurodermatitis. Common triggers for the development of the disease include psychological distress, and local environmental problems such as heat, sweating, and excess dryness. Lichen simplex chronicus may also develop as a superimposed condition in the presence of other anogenital diseases such as candidiasis, psoriasis, lichen sclerosus, tinea cruris, and neoplasia. Lichen simplex chronicus frequently persists as an itch-scratch cycle, even when environmental triggers are removed and the underlying disease is treated. For this reason, successful therapy requires attention not only to trigger factors, but also to repair of the damaged barrier layer, reduction in inflammation, and breakup of the itch-scratch cycle.

Vulvar Contact Dermatitis: Effect of a Treatment with a Anti-Inflammatory, Moisturizing and Healing Product on the Course of the Disease

“…A detailed history should explore whether the patient has adopted any new cleansing routines, has been using new personal care products, douches, perfumes, undergarments and topical medications. Excessive cleansing of the vulvar skin may precipitate to an irritant dermatitis [5].…”

Is it relevant a correct intimate cleansing in the treatment of vulvar dermatosis?

“…LSC is caused by persistent itching and scratching of vulvar skin, resulting in a thickened leathery appearance. It is thought to be an atopic disorder in many cases and may also arise in normal skin [6]. In both the disorders, the area involved may vary from a single small to the entire region of vulva, perineum, and perianus [7].…”

Vulvar Dermatoses: Effect of a Synergistic Treatment with a Moisturizing and Healing Product on the Course of the Disease

“…The disease can be considered an atopic disorder in many cases and may arise in normal skin as a result of psychological stress or environmental factors [3]. On examination, LSC presents as erythematous, lichenified plaques with overlying excoriation, and linear fissures may be found at the skin folds.…”