Lichen Sclerosus et Atrophicus

Ridley, C. M.

doi:10.1001/archderm.1987.01660280059022

Cited by 36 publications

(14 citation statements)

References 16 publications

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“…Vulvar lichen sclerosus (LS) is uncommon but well recognized in prepubertal girls. It has been a widely held belief that it is likely to resolve at puberty, however Ridley disputed this as early as 1987 (1). A recently published study has further questioned this belief (2).…”

mentioning

confidence: 99%

Childhood Onset Vulvar Lichen Sclerosus Does Not Resolve at Puberty: A Prospective Case Series

Smith

Fischer

2009

Pediatric Dermatology

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When vulvar lichen sclerosus occurs in prepubertal children it is widely believed that it is likely to remit at puberty. However when it occurs in adult women it is accepted that remission is unlikely and that in addition untreated or inadequately treated disease may be complicated by significant disturbance of vulvar architecture and less commonly squamous cell carcinoma. Our database reveals 18 girls who developed lichen sclerosus prior to puberty who are now adolescents or young adults. Twelve have remained under surveillance and the other six patients have been lost to follow-up. We report a prospective series of these 12 patients. Three patients have achieved complete remission sustained for three or more years, all prior to menarche. Nine patients, or 75% of the cohort, who still had active lichen sclerosus at puberty continue to require maintenance therapy after menarche. Of the 12, six have had significant disturbance of vulvar architecture. The concept that prepubertal lichen sclerosus resolves at puberty would appear not to be true in the majority of patients. Even when diagnosed early and treated effectively, childhood onset lichen sclerosus may be complicated by distortion of vulvar architecture.

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confidence: 99%

Childhood Onset Vulvar Lichen Sclerosus Does Not Resolve at Puberty: A Prospective Case Series

Smith

Fischer

2009

Pediatric Dermatology

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“…Most cases occur in postmenopausal women, and approximately 1% to 15% in prepubertal girls (4)(5)(6). Genital LSA in boys is much less frequent than in girls, although it may be the main cause of scarring phimosis requiring circumcision in these children (7,8).…”

Section: Discussionmentioning

confidence: 99%

Persistent Erythema Infectiosum‐Like Rash as a Prodrome of Acute Lymphocytic Leukemia

Sahn

Bluestein²,

Oliva

1994

Pediatric Dermatology

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“…2,3 We believe that the original observer of the association was the late Marjorie Ridley. 4,5 Our interpretation of most of the cases reported in the literature, including this latest one, is that PEKMB is a complication of chronic, untreated or burnt-out LSc, with a significant potential for frank squamous carcinogenesis.…”

mentioning

confidence: 92%

“…Electrosurgery, and in particular, monoterminal electrocautery, can result in pacemaker malfunction by oversensing, inhibiting firing or triggering of rapid firing, device reprogramming, battery depletion, or direct damage to the device. 4 There are few articles in the dermatological literature for the management of these high-risk patients. In one published report, only a small percentage of the Mohs surgeons in the USA were reported to be incorporating the evaluation of these devices in their management, with wide variation in the types of precautions that they undertook.…”

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confidence: 99%