Lichen sclerosus and the Kobner phenomenon

Todd, P.; Halpern, S.M.; Kirby, John D.; Pembroke, A.C.

doi:10.1111/j.1365-2230.1994.tb01183.x

Cited by 53 publications

(35 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2,3 In a closer parallel to this case, the Köbner response has been reported over a strawberry naevus. 12 It has also been suggested that the Köbner response may contribute to vulvar lichen sclerosus.…”

Section: Discussionsupporting

confidence: 52%

“…1 Chronic pressure has previously been reported to act as a trigger for the Köbner response in lichen sclerosus. 2,3 Forces to which the skin is subject include friction, stretching, compression, vibration and penetration. 4 A woman with generalized lichen sclerosus displaying lesions of lichen sclerosus along a varicosed leg vein is presented.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Köbnerization in a woman with generalized lichen sclerosus

Noakes

Spelman

2004

Aust J Dermatology

View full text Add to dashboard Cite

A 52-year-old woman presented with an 18-month history of genital and extragenital lichen sclerosus. In addition to the classical genital findings, lesions of lichen sclerosus were present over her back, chest and the medial aspect of her right thigh and leg. On her right thigh and extending to her right leg, lesions of lichen sclerosus displaying the Köbner response were noted over the course of a varicosed long saphenous vein. There were no features of varicose dermatitis in the region displaying the Köbner response. It is proposed that the ambulatory venous pressure within the vein acted as a stimulus for the Köbner response.

show abstract

Section: Discussionsupporting

confidence: 52%

Section: Introductionmentioning

confidence: 99%

Köbnerization in a woman with generalized lichen sclerosus

Noakes

Spelman

2004

Aust J Dermatology

View full text Add to dashboard Cite

show abstract

“…This isomorphic response has been well described in psoriasis, 3 lichen sclerosus, 4 and lupus erythematosus 5 -all of which produce lesions similar to the primary condition in either apparently normal skin following trauma or exposure to strong sunlight or in areas of contact dermatitis, scars, and so on. However, this is the first report describing a Koebner-like phenomenon in a patient with myelodysplastic syndrome.…”

Section: Discussionmentioning

confidence: 81%

An unusual cutaneous manifestation of myelodysplastic syndrome: "pseudo-Koebner phenomenon".

Dasgupta

Fairham²,

Womack³

et al. 1998

J Clin Pathol

View full text Add to dashboard Cite

An unusual and hitherto unreported complication of myelodysplastic syndrome is reported: the "pseudo-Koebner phenomenon." The skin lesions were characterised by exuberant "fleshy" masses at the sites of intravenous cannulation and skin trauma, and by histological evidence of chronic inflammation with focal necrosis and abscess formation. No evidence of dermal infiltration by malignant haemopoietic cells was seen. The exact aetiopathology of the phenomenon is unclear but an inappropriate and exaggerated inflammatory response owing to aberrant mediator mechanisms that are known to occur in some cases of myelodysplastic syndrome may be implicated. (J Clin Pathol 1998;51:860-861)

show abstract

“…[14] Local factors such as friction, trauma, or rubbing may cause Koebner phenomenon. [15] Oxidative stress may also be responsible for sclerosis, autoimmunity, and carcinogenesis in case of LS. [16]…”

Section: Etiologymentioning

confidence: 99%

Vulvar lichen sclerosus et atrophicus

Nair

2017

J Mid-life Health

View full text Add to dashboard Cite

Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis characterized by ivory-white plaques or patches with glistening surface commonly affecting the vulva and anus. Common symptoms are irritation, soreness, dyspareunia, dysuria, and urinary or fecal incontinence. Anogenital lichen sclerosus (LS) is characterized by porcelain-white atrophic plaques, which may become confluent extending around the vulval and perianal skin in a figure of eight configuration. Thinning and shrinkage of the genital area make coitus, urination, and defecation painful. LS is not uncommon in India and present as an itchy vulvar dermatosis which a gynecologist may mistake for candidal vulvovaginitis. There is often a delay in diagnosis of VLS due to its asymptomatic nature and lack of awareness in patients as well as physicians. Embarrassment of patients due to private nature of the disease and failure to examine the genital skin properly are the other reasons for delay in diagnosis. There is no curative treatment for LS. Various medications available only relieve the symptoms. Chronic nature of the disease affects the quality of life. Proper and regular follow-up is required as there are chances of the development of squamous cell carcinoma.

show abstract

Lichen sclerosus and the Kobner phenomenon

Cited by 53 publications

References 8 publications

Köbnerization in a woman with generalized lichen sclerosus

Köbnerization in a woman with generalized lichen sclerosus

An unusual cutaneous manifestation of myelodysplastic syndrome: "pseudo-Koebner phenomenon".

Vulvar lichen sclerosus et atrophicus

Contact Info

Product

Resources

About