Lichen planus: Oral manifestations and suggested treatments

Dusek, J; Frick, William G.

doi:10.1016/0278-2391(82)90321-4

Cited by 30 publications

(4 citation statements)

References 18 publications

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“…The benefits of intralesional corticosteroids are now well known and described (Randall and Cohen, 1974). Dusek and Frick (1982) recommend a 5% mixture be made with lidocaine to lessen the pain of the injections. Zegarelli (1983) combined the use of topical and weekly intralesional corticosteroids in seven patients.…”

Section: A Topicalmentioning

confidence: 99%

The Therapy of Oral Lichen Planus

Eisen

1993

Critical Reviews in Oral Biology & Medicine

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Oral lichen planus is a chronic mucocutaneous disease that is relatively common. Although many patients are asymptomatic and require no therapy, those who exhibit atrophic and erosive lesions are often a challenge to treat. All therapies are palliative, and none is effective universally. Currently employed treatment modalities include corticosteroids administered topically, intralesionally, or systemically. Alternative therapies include topical and systemic retinoids, griseofulvin, Cyclosporine, and surgery. Other medical treatments and experimental modalities, including mouth PUVA, have been reported to be effective. Controversy concerning the efficacy of all these treatments suggests that oral lichen planus is a heterogeneous disorder. Eliminating lichenoid drug eruptions, candidiasis, trauma, contact mucositis, and emotional stress may play a role in the management of these patients. This article is a review of the many treatments and measures that have been employed in the management of patients with oral lichen planus.

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Section: A Topicalmentioning

confidence: 99%

The Therapy of Oral Lichen Planus

Eisen

1993

Critical Reviews in Oral Biology & Medicine

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“…Lichen planus (LP) is a relatively common disorder of the stratified squamous epithelia (Duske and Frick, 1982;Scully and El-Kom, 1985;Conklin and Blasberg, 1987;Jungell, 1991). Most dental practitioners must see patients with LP, but not all recognize this.…”

Section: Introductionmentioning

confidence: 99%

Update On Oral Lichen Planus: Etiopathogenesis and Management

Scully

Beyli²,

Ferreiro

et al. 1998

Critical Reviews in Oral Biology & Medicine

467

461

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Lichen planus (LP) is a relatively common disorder of the stratified squamous epithelia, which is, in many ways, an enigma. This paper is the consensus outcome of a workshop held in Switzerland in 1995, involving a selection of clinicians and scientists with an interest in the condition and its management. The oral (OLP) eruptions usually have a distinct clinical morphology and characteristic distribution, but OLP may also present a confusing array of patterns and forms, and other disorders may clinically simulate OLP. Lesions may affect other mucosae and/or skin. Lichen planus is probably of multifactorial origin, sometimes induced by drugs or dental materials, often idiopathic, and with an immunopathogenesis involving T-cells in particular. The etiopathogenesis appears to be complex, with interactions between and among genetic, environmental, and lifestyle factors, but much has now been clarified about the mechanisms involved, and interesting new associations, such as with liver disease, have emerged. The management of lichen planus is still not totally satisfactory, and there is as yet no definitive treatment, but there have been advances in the control of the condition. There is no curative treatment available; immunomodulation, however, can control the condition. Based on the observed increased risk of malignant development, OLP patients should be offered regular follow-up examination from two to four times annually and asked to report any changes in their lesions and/or symptoms. Follow-up may be particularly important in patients with atrophic/ulcerative/erosive affections of the tongue, the gingiva, or the buccal mucosa. Much more research is required into the genetic and environmental aspects of lichen planus, into the premalignant potential, and into the possible associations with chronic liver, and other, disorders. More clinical studies are required into the possible efficacy of immunomodulatory drugs such as pentoxifylline and thalidomide.

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“…The prevalence of lichen planus in general population is of the order of 0.9 to 1.2 per cent [25]. Hellier (1940) in a study of environment and skin diseases reported that OLP occurred between 0.1 to 1.25 percent of the dermatological out patients.…”

Section: Epidemiology Prevalencementioning

confidence: 99%

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2018

BJSTR

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Lichen planus: Oral manifestations and suggested treatments

Cited by 30 publications

References 18 publications

The Therapy of Oral Lichen Planus

The Therapy of Oral Lichen Planus

Update On Oral Lichen Planus: Etiopathogenesis and Management

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