Lichen planus and hepatitis C virus prevalence and clinical presentation in Egypt

Amer, M.E. Parera; El-Harras, M; Attwa, Enayat; Raslan, Suzane A

doi:10.1111/j.1468-3083.2007.02145.x

Cited by 12 publications

(21 citation statements)

References 8 publications

(7 reference statements)

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“…To uncover possible publication bias, we assessed publication bias by using an inverted funnel plot in which the OR was plotted on a logarithmic scale on the vertical axis against the number of participants in each study on the horizontal axis (the standard error from each study). †References 12,15,[18][19][20]23,24,[33][34][35]57,62,72,43,44,[46][47][48][49][50][51]53,55,[57][58][59][60][61][62][63][66][67][68][69][70][71][72][73][74][75]15,18,21,22,[24][25][26][27]29,33,…”

Section: Discussionmentioning

confidence: 99%

Hepatitis C Virus and Lichen Planus

Liu¹,

Songpo²,

Wen³

et al. 2009

Arch Dermatol

129

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Section: Discussionmentioning

confidence: 99%

Hepatitis C Virus and Lichen Planus

Liu¹,

Songpo²,

Wen³

et al. 2009

Arch Dermatol

129

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“…Case-control studies falling within the inclusion criteria were 46. One study [20] was not included because HCV prevalence was not assessed through anti-HCV antibodies, while two studies [21,22] were excluded because control subjects were not examined for anti-HCV antibodies. The remaining primary studies, listed along with the present study, in Table 4, amounted to 43 [6,8,13,14,.…”

Section: Meta-analysis Of Observational Studiesmentioning

confidence: 99%

The magnitude of the association between hepatitis C virus infection and oral lichen planus: meta-analysis and case control study

et al. 2011

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Although hepatitis C virus (HCV) infection is associated with oral lichen planus (OLP), a case-control study and a meta-analysis were designed to investigate the magnitude of such an association. A total of 413 presumptive OLP patients (18-75 years) who referred to a dental clinic in Rasht (Iran) were consecutively selected. OLP was diagnosed clinically (typical forms) and histologically (atypical forms) by a calibrated examiner. A total of 487 adults (20-77 years) attending the same dental clinic were the controls. The two groups were homogeneous in terms of age, gender and occupation. Subjects were tested for anti-HCV antibodies. The odds ratio (OR) for OLP attributable to HCV infection was non-significant [OR 1.2, 95% confidence interval (95CI) 0.3-4.8], suggesting that the association between HCV and OLP was weak in the Iranian context. Meta-analysis of observational studies characteristics of primary studies were that cases were diagnosed clinically (only typical forms) and histologically and exposure was assessed through anti-HCV antibodies. Exposed/unexposed cases/controls were extracted and zero values were appropriately transformed. As much as 44 studies, including the present, were located. Publication bias could not be totally excluded. The pooled OR, estimated using the random-effect model, was 2.8 (95CI 2.4-3.2). Sensitivity analysis confirmed the robustness of results. Subgroup analysis showed non-significant differences between American/European and Asian/African studies. The fraction of global OLP cases associated with HCV (population attributable fraction) was 2.1% (95CI 1.9-2.2%). Although HCV and OLP were significantly associated, the majority of OLP patients were not affected by HCV.

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“…As both hepatitis B and C are associated with chronic inflammation and aberrant immune response, it is possible that both viruses may independently trigger or exacerbate lichen planus. The association between lichen planus and hepatitis C has been a matter of numerous studies with contradictory results 3,7–22 . Many biases were alleged to appear in some of the studies including selection bias, referral bias and misclassification.…”

Section: Introductionmentioning

confidence: 99%

A study on the association with hepatitis B and hepatitis C in 1557 patients with lichen planus

Birkenfeld

Dreiher

Weitzman

et al. 2011

Acad Dermatol Venereol

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Lichen planus and hepatitis C virus prevalence and clinical presentation in Egypt

Abstract: leukaemia followed by ATRA-induced pseudotumour cerebri. Br J Haematol 1996; 92: 937-940. 5 Fedotin MS. Hypervitaminosis causing pseudotumor cerebri.

Cited by 12 publications

References 8 publications

Hepatitis C Virus and Lichen Planus

Hepatitis C Virus and Lichen Planus

The magnitude of the association between hepatitis C virus infection and oral lichen planus: meta-analysis and case control study

A study on the association with hepatitis B and hepatitis C in 1557 patients with lichen planus

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