Lichen planopilaris related to imatinib therapy with good response to oral doxycycline

Abstract

Lichen planopilaris related to imatinib therapy with good response to oral doxycycline 1 | INTRODUCTION Targeted agents offer a more precise oncologic treatment but they are not free of side effects. Imatinib is a tyrosine kinase inhibitor mainly used to treat chronic myeloid leukemia and gastrointestinal stromal tumor (GIST) among other conditions. Alopecia related to imatinib is an unusual adverse effect but it may have high negative impact on patient's quality of life. 1 2 | CASE REPORT An 86-year-old woman was remitted to our department for scalp itching and decreased hair density that started 2 months before. She was diagnosed with pelvic GIST tumor with peritoneal involvement and imatinib 300 daily was started 6 months ago. She first began with