Lichen aureus with pseudolymphomatous infiltrate

Kolm, Isabel; Buset, C.; Flury, Ursula; Nosek, Daniel; Kazakov, Dmitry V.; Kempf, Werner

doi:10.1111/cup.13948

Cited by 7 publications

(13 citation statements)

References 20 publications

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“…Unlike the three patients described by Kolm et al, 1 the inflammation in our patient was mild, and there were poikilodermatous features such as dermal fibrosis and epidermal atrophy. The lower density of lymphocytes and focal erythrocytes extravasation in our case can be explained by the more than 1‐year duration of symptoms.…”

Section: Figurecontrasting

confidence: 82%

“…We wish to commend Kolm et al, 1 for the high quality of their case series. The topic is critical in dermatopathology, and there are only a few previously published papers on the subject.…”

Section: Figurementioning

confidence: 99%

“…T‐cell‐associated antigen (CD3, CD7) relations were not preserved, and there was a lack of CD7‐positivity. In the three cases described by Kolm et al, CD7 testing was not performed, and the T‐cell‐associated antigen relations were evaluated using CD3 and CD5 1 …”

Section: Figurementioning

confidence: 99%

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Lichen aureus with pseudolymphomatous infiltrate: Other histopathological aspects and the importance of clinical‐pathological correlation

et al. 2021

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Section: Figurecontrasting

confidence: 82%

“…We wish to commend Kolm et al, 1 for the high quality of their case series. The topic is critical in dermatopathology, and there are only a few previously published papers on the subject.…”

Section: Figurementioning

confidence: 99%

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Lichen aureus with pseudolymphomatous infiltrate: Other histopathological aspects and the importance of clinical‐pathological correlation

et al. 2021

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“…Compared to other types of PPD—in which the inflammatory infiltrate normally is confined to the papillary dermis—GPPD generally shows a deeper extension of the inflammatory infiltrate, which additionally can cause diagnostic problems. A deeper infiltrate, however, can be observed in PPD such as in the recently reported pseudolymphomatous variant of lichen aureus 1 …”

Section: Discussionmentioning

confidence: 89%

“…The typical histopathology of PPD shows a perivascular lymphocytic infiltrate in the papillary dermis, endothelial swelling, accompanied by extravasated erythrocytes and hemosiderin deposits in the upper dermis 1‐3 …”

Section: Introductionmentioning

confidence: 99%

Granulomatous pigmented purpuric dermatosis: Clinical and histopathologic findings in a series of nine cases

2022

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We report the largest case series to date of granulomatous pigmented purpuric dermatosis (GPPD), a rare variant of pigmented purpuric dermatoses (PPD). GPPD can cause diagnostic difficulties as it can be mistaken clinically and histopathologically with numerous inflammatory and infectious dermatoses or even cutaneous T‐cell lymphoma. We compared the histopathological findings of nine cases of GPPD with a control group consisting of 10 randomly selected PPD of other subtypes. GPPD seems to predominantly affect the lower extremities of adult male patients; a clear association with hyperlipidemia or other systemic conditions could not be confirmed. Histopathologically, GPPD is characterized by a dermal histiocyte‐rich interstitial infiltrate with or without granuloma formation, thickened capillaries, extravasated erythrocytes, and/or hemosiderin deposits. In contrast to other forms of PPD, the inflammatory infiltrate of GPPD can extend to the mid or deep dermis and the admixed lymphocytic infiltrate is mainly composed of CD8+ T‐cells.

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Pigmented Purpuric Dermatosis of the Hand: Clinicopathologic Analysis of Six Cases With Review of the Literature

Runge

Nakamura²,

Sullivan³

et al. 2022

The American Journal of Dermatopathology

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Pigmented purpuric dermatosis (PPD) is a group of skin disorders characterized by red, brown, or golden macules and patches with cayenne pepper-like spots. Classic histopathologic features include a perivascular lymphocytic infiltrate with associated erythrocyte extravasation and hemosiderin deposition. Although PPD most commonly affects the lower extremities, upper extremity involvement has been infrequently reported. Cases involving the hands are particularly rare. We present 6 new cases of PPD involving the hand and review 17 previously reported cases in the literature. All cases in our series were unilateral and localized to the dorsum of the hand. PPD was considered clinically in only 2 of these cases. Histopathologic examination revealed hallmark features of PPD, namely a superficial perivascular lymphocytic infiltrate and extravasated erythrocytes. Previous reports of PPD involving the hand described concurrent involvement of other anatomic sites in most cases; only 4 cases (24%) were confined to the hands. Histopathologic descriptions of these reported cases were compatible with PPD. In sum, our series describes a unique and rare clinical presentation of PPD confined to the unilateral dorsal hand. Because of the unusual presentation, biopsy is often required for accurate diagnosis.

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Lichen aureus with pseudolymphomatous infiltrate

Cited by 7 publications

References 20 publications

Lichen aureus with pseudolymphomatous infiltrate: Other histopathological aspects and the importance of clinical‐pathological correlation

Lichen aureus with pseudolymphomatous infiltrate: Other histopathological aspects and the importance of clinical‐pathological correlation

Granulomatous pigmented purpuric dermatosis: Clinical and histopathologic findings in a series of nine cases

Pigmented Purpuric Dermatosis of the Hand: Clinicopathologic Analysis of Six Cases With Review of the Literature

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