Lichen amyloidosis with face involvement

Gül, Ülker; Kılıç, Arzu; Bilgili, Seher; Gönül, Miizeyyen; Çakmak, Seray Külcü; Demiriz, Murat

doi:10.1111/j.1365-4632.2008.03705.x

Cited by 5 publications

(5 citation statements)

References 9 publications

(12 reference statements)

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“…Histologically, LA appears as eosinophilic amorphous deposits in the papillary dermis with hyperkeratosis and acanthosis of the epidermis [5,7]. Although it is commonly an isolated finding, LA can be associated with other diseases such as atopic dermatitis, mycosis fungoides, lichen planus, HIV, multiple endocrine neoplasia type 2A, angiolymphoid hyperplasia with eosinophilia, ankylosing spondylitis, autoimmune thyroiditis, and hyperthyroidism [7,[10][11][12][13].…”

Section: Case Discussionmentioning

confidence: 99%

Clinical resolution of generalized lichen amyloidosis with dupilumab: a new alternative therapy

Humeda¹,

Beasley²,

Calder³

2020

Dermatology Online Journal

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Section: Case Discussionmentioning

confidence: 99%

Clinical resolution of generalized lichen amyloidosis with dupilumab: a new alternative therapy

Humeda¹,

Beasley²,

Calder³

2020

Dermatology Online Journal

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“…An association between LA and other diseases such as atopic dermatitis, lichen planus, mycosis fungoides, chronic urticaria, HIV infection, multiple endocrine neoplasia type 2A, and angiolymphoid hyperplasia with eosinophilia have been defined [ 3 , 4 , 6 , 11 ]. A case of LA associated with ankylosing spondylitis and autoimmune thyroiditis has been reported previously [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

Generalized lichen amyloidosis and hyperthyroidism: coincidence or association

Gönül

Çakmak²,

Kayaçatin³

2013

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A 76-year-old white man presented with severe pruritic eruption on both of the extremities and lumbar area for 2 years. The dermatological examination showed multiple, 1–2 mm sized, hyperpigmented and hyperkeratotic papules which coalesced to form poorly delineated plaques spread on the lumbosacral area, lateral and extensor surfaces of thighs, arms and forearms. The histopathological examination revealed eosinophilic amorphous material in papillary dermis that was stained positively with crystal violet stain. The patient was diagnosed as generalized lichen amyloidosis (LA) clinically and histopathologically. Routine laboratory tests were within normal limits except thyroid function tests. The thyroid stimulating hormone level was decreased, while the thyroxine level was increased. Ultrasonography showed enlarged and heterogeneous thyroid gland. Thyroid autoantibodies were within normal limits. An association between LA and other diseases such as atopic dermatitis, lichen planus, mycosis fungoides, chronic urticaria, HIV infection, multiple endocrine neoplasia type 2A, and angiolymphoid hyperplasia with eosinophilia have been defined. However, there is no reported LA case associated with hyperthyroidism in the literature. We think that the same etiologic factor might have triggered both diseases, or hyperthyroidism, by causing the itching, might have induced the occurrence or spread of LA.

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“…Considering the apoptosis and secretory PLA pathogenesis theories, 2 combined with the identification of degraded keratin, amyloid P component and secondary immunoglobulin, 2,4,7,8 chronic trauma appears to be the main factor associated with sporadic PLA; 2,4,6 however, we did not find any traumatic factors in our patients. PLA is not associated with drug reactions, so it cannot to be associated with ART use.…”

Section: Discussionmentioning

confidence: 53%

“…In the skin, the most common affected areas are the upper/lower extremities 1,2,7 and the trunk. 1 Face lesions, 6 including one case in the upper lip, 8 have been also described. In HIV patients, there are few PLA reports, 9–11 all of them describing pruritic skin papules without a causal factor or systemic involvement.…”

Section: Discussionmentioning

confidence: 99%