Lhermitte′s Sign: The Current Status

Abstract

Lhermitte's sign was described by Marie and Chatelin and named after Jean Lhermitte. This sign is mostly described as an electric shock like condition by some patients of multiple sclerosis. This sensation occurs when the neck is moved in a wrong way or rather flexed. It can also travel down to the spine, arms, and legs, and sometimes the trunk. Demyelination and hyperexcitability are the main pathophysiological reasons depicted for the Lhermitte's sign. Other causes for Lhermitte's sign include transverse myelitis, behçet's disease, trauma, etc. This article reviews the Lhermitte's sign, its history, and its etiopathophysiology. Very few studies are available on Lermitte's sign and more research need to be done on the same to ensure its sensitivity and specificity.

Conversion Disorder (Functional Neurological Symptom Disorder) Masquerading as Multiple Sclerosis: A Case Report

“…The onset is often polysymptomatic and the typical patient is a young adult with two or more clinically distinct episodes of central nervous system dysfunction with at least partial resolution with time. Proposed criteria for conversion disorder in the DSM-5 include "one or more symptoms of altered voluntary or sensory function" ( Table 3 adapted from [13]). The clinical symptoms, "provide evidence of incompatibility between the symptom and recognized neurological or medical conditions," and "is not better explained by another medical or mental disorder" ( Table 4).…”

Complicaciones de la radioterapia: fenómeno de Lhermitte gatillado por calor. Caso clínico

“…Al indagar sobre estímulos específicos del dolor en los pacientes que sufren FL como consecuencia de radioterapia, sólo se describen los movimientos cervicales, que además de la flexión, puede ser la extensión y/o rotación [1][2][3][4] . Se debe tener en consideración que existen otras causas del fenómeno, y que el paciente pudiera manifestar el síntoma a raíz de alguna de ellas: esclerosis múltiple (EM) (16% de los pacientes reportan el síntoma), quimioterapia (neurotoxicidad por cisplatino o figura 1.…”

Paroxysmal Symptoms in Multiple Sclerosis—A Review of the Literature

“…It is defined as a short-lasting electric-like sensation felt at the back of the neck radiating to the lower parts of the body following neck flexion and disappearing on resuming normal posture [ 54 ]. Most MS patients cope well with this symptom, when problematic, neck braces/collars have been used to decrease neck movements that provoke LS [ 55 ]. Carbamazepine had an immediate symptomatic effect in 3 patients with LS [ 56 ].…”