2003
DOI: 10.1074/jbc.m302681200 View full text |Buy / Rent full text
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Abstract: The type 1 carbohydrate chain, Gal␤1-3GlcNAc, is synthesized by UDP-galactose:␤-N-acetylglucosamine ␤1,3-galactosyltransferase (␤3Gal-T). Among six ␤3Gal-Ts cloned to date, ␤3Gal-T5 is an essential enzyme for the synthesis of type 1 chain in epithelium of digestive tracts or pancreatic tissue. It forms the type 1 structure on glycoproteins produced from such tissues. In the present study, we found that the transcriptional regulation of the ␤3Gal-T5 gene is controlled by homeoproteins, i.e. members of caudal-re… Show more

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