Levofloxacin loaded clove essential oil nanoscale emulsion as an efficient system against Pseudomonas aeruginosa biofilm

Razdan, Karan; Gondil, Vijay Singh; Chhibber, Sanjay; Singh, Kamalinder K.; Sinha, Vivek Ranjan

doi:10.1016/j.jddst.2021.103039

Cited by 5 publications

(2 citation statements)

References 40 publications

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“…Moreover, relative conductivity, leakage of proteins, and nucleic acids have all confirmed that the antimicrobial effect of the microemulsion was more advantageous than that of a single antimicrobial component. Razdan et al reported that levofloxacin could enhance the antibacterial activity of clove oil nano-emulsions and the stronger disrupting effect of the nano-emulsion on the biofilm of P. aeruginosa [ 48 ]. Moreover, Almasi et al demonstrated that a microemulsion of thyme essential oil and propionic or acetic acid may have synergistic effects [ 49 ].…”

Section: Resultsmentioning

confidence: 99%

Microemulsion of Cinnamon Essential Oil Formulated with Tea Polyphenols, Gallic Acid, and Tween 80: Antimicrobial Properties, Stability and Mechanism of Action

et al. 2022

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The objective of this article was to combine tea polyphenols, gallic acid, and cinnamon essential oil to construct a natural extract-complex microemulsion system (NMs) with good antibacterial activity, antioxidant activity, and stability, as well as low irritation. NMs were characterized by particle size distribution, electrical conductivity, and light transmittance. The stability, as well as the antimicrobial, antioxidant, irritation, and antimicrobial mechanisms, of NMs were also studied. The results showed that NMs had a significant antimicrobial function against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and Aspergillus brasiliensis. The minimum inhibitory concentrations were 156 μg/mL, 62.5 μg/mL, 125 μg/mL, 250 μg/mL, and 125 μg/mL, respectively. Through the cell membrane permeability test and growth curve test of bacteria and fungi, we concluded that the NMs’ mechanism of action on bacteria and fungi could be interpreted as NMs mainly altering the permeability of cell membranes to inhibit the growth of bacteria and fungi. The results of this study have important implications for utilizing plant extracts as natural preservatives for food and cosmetics.

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Section: Resultsmentioning

confidence: 99%

Microemulsion of Cinnamon Essential Oil Formulated with Tea Polyphenols, Gallic Acid, and Tween 80: Antimicrobial Properties, Stability and Mechanism of Action

et al. 2022

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“…LFX-NE inhibited quorum sensing activity responsible for biofilm formation and was able to eradicate pre-formed biofilms of P. aeruginosa as demonstrated by laser scanning microscopy and field emission scanning electron microscopy. They revealed high antibacterial activity with 16-fold and 8-fold reduction in minimum inhibitory concentration against P. aeruginosa and Escherichia coli and Klebsiella pneumoniae , respectively [ 85 ].…”

Section: Nanomedicine-based Advancement In Sepsismentioning

confidence: 99%

Recent nanoengineered diagnostic and therapeutic advancements in management of Sepsis

Soni

Handa

Singh

2022

Journal of Controlled Release

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Inhibition of biofilm formation, quorum sensing and virulence factor production in Pseudomonas aeruginosa PAO1 by selected LasR inhibitors

Vetrivel

Dhandapani

et al. 2023

Int Microbiol

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Levofloxacin loaded clove essential oil nanoscale emulsion as an efficient system against Pseudomonas aeruginosa biofilm

Cited by 5 publications

References 40 publications

Microemulsion of Cinnamon Essential Oil Formulated with Tea Polyphenols, Gallic Acid, and Tween 80: Antimicrobial Properties, Stability and Mechanism of Action

Microemulsion of Cinnamon Essential Oil Formulated with Tea Polyphenols, Gallic Acid, and Tween 80: Antimicrobial Properties, Stability and Mechanism of Action

Recent nanoengineered diagnostic and therapeutic advancements in management of Sepsis

Inhibition of biofilm formation, quorum sensing and virulence factor production in Pseudomonas aeruginosa PAO1 by selected LasR inhibitors

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