Leveraging Informatics, Mobile Health Technologies and Biobanks to Treat Each Patient Right

Hirsch, Bradford R.; Abernethy, Amy P.

doi:10.2217/pme.12.102

Cited by 5 publications

(3 citation statements)

References 56 publications

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“…During that coding process, the coders determined that 30 of the publications did not meet the eligibility criteria. Thus, the final corpus comprised of 79 publications 4,9,12‐88 …”

Section: Methodsmentioning

confidence: 99%

Clarifying the concept of a learning health system for healthcare delivery organizations: Implications from a qualitative analysis of the scientific literature

Easterling

Perry

Woodside

et al. 2021

Learning Health Systems

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The "learning health system" (LHS) concept has been defined in broad terms, which makes it challenging for health system leaders to determine exactly what is required to transform their organization into an LHS. This study provides a conceptual map of the LHS landscape by identifying the activities, principles, tools, and conditions that LHS researchers have associated with the concept. Through a multi-step screening process, two researchers identified 79 publications from PubMed (published before January 2020) that contained information relevant to the question, "What work is required of a healthcare organization that is operating as an LHS?" Those publications were coded as to whether or not they referenced each of 94 LHS elements in the taxonomy developed by the study team. This taxonomy, named the Learning Health Systems Consolidated Framework (LHS-CF), organizes the elements into five "bodies of work" (organizational learning, translation of evidence into practice, building knowledge, analyzing clinical data, and engaging stakeholders) and four "enabling conditions" (workforce skilled for LHS work, data systems and informatics technology in place, organization invests resources in LHS work, and supportive organizational culture). We report the frequency that each of the 94 elements was referenced across the 79 publications. The four most referenced elements were: "organization builds knowledge or evidence," "quality improvement practices are standard practice," "patients and family members are actively engaged," and "organizational culture emphasizes and supports learning." By dissecting the LHS construct into its component elements, the LHS-CF taxonomy can serve as a useful tool for LHS researchers and practitioners in defining the aspects of LHS they are addressing. By assessing how often each element is referenced in the literature, the study provides guidance to health system leaders as to how their organization needs to evolve in order to become an LHS -while also recognizing that each organization should emphasize elements that are most aligned with their mission and goals.

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“…During that coding process, the coders determined that 30 of the publications did not meet the eligibility criteria. Thus, the final corpus comprised of 79 publications 4,9,12‐88 …”

Section: Methodsmentioning

confidence: 99%

Clarifying the concept of a learning health system for healthcare delivery organizations: Implications from a qualitative analysis of the scientific literature

Easterling

Perry

Woodside

et al. 2021

Learning Health Systems

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“…Obesity and response to exercise [ ies embedded in electronic medical records (EMRs), may provide the most rational solution to this problem [9,21]. Citizen science that assesses dietary as well as pharmacological interventions and integrates genomics and social networks is an untapped route to progress in the field of hypertension management [22,23].…”

Section: Prkca Rs16960228mentioning

confidence: 99%

“…In the future this is likely to demonstrate further links with the autonomic nervous system, the importance of diurnal variation, environmental and stressful stimuli and should reveal otherwise imperceptible patterns in clinical data (Figure 2) [92]. These integrated biobank initiatives need to be collaborative, locally supported and viewed as part of clinical care rather than research [21].…”

Section: Pharmacogenomics and Chronotherapymentioning

confidence: 99%

Personalized Hypertension Management in Practice

Gladding

Patrick²,

Manley³

et al. 2015

Per. Med.

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The revolution occurring in genomic and personalized medicine is likely to have a significant impact on the management of hypertension. However, from the perspective of translating new knowledge into clinical practice, progress has been slow. This review article summarizes recent advances in hypertension-related diagnostics while also offering new perspective on hypertension management for the future. Such new perspectives will likely require a paradigm shift toward more integrated and holistic approaches for better prevention and treatment of hypertension in both individuals and the population as a whole.

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Comparative Effectiveness Research: Moving Medical Oncology Forward

Hirsch

Zafar

2014

Seminars in Radiation Oncology

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Leveraging Informatics, Mobile Health Technologies and Biobanks to Treat Each Patient Right

Cited by 5 publications

References 56 publications

Clarifying the concept of a learning health system for healthcare delivery organizations: Implications from a qualitative analysis of the scientific literature

Clarifying the concept of a learning health system for healthcare delivery organizations: Implications from a qualitative analysis of the scientific literature

Personalized Hypertension Management in Practice

Comparative Effectiveness Research: Moving Medical Oncology Forward

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