Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches
Konstantina Morali,
Gloria Giacomello,
Michela Vuono
et al.
Abstract:Dendritic cells (DC) are professional antigen‐presenting cells involved in promoting and controlling immune responses. Different subsets of DC, named tolerogenic (tol)DC, play a critical role in the maintenance of tissue homeostasis and in fostering tolerance. These unique skills make tolDC especially attractive for strategies aimed at re‐establishing/inducing tolerance in immune‐mediated conditions. The generation of potent tolDC in vitro from peripheral blood monocytes has seen remarkable advancements. TolDC… Show more
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