Levels of some antiviral antibodies in patients with different serum content of total cholesterol

Abstract

We measured the content of specific antibodies to some viral antigens (herpes, cytomegalovirus, measles, rubella, mumps) in patients with different levels of total serum cholesterol. The levels of IgG to the most prevalent viral infections (measles, herpes, rubella) were higher in patients with 6-7 mmol/liter total serum cholesterol (mild and moderate hypercholesterolemia). These data confirm the relationship between the status of the lipid transporting system and antiviral immunity and the existence of a cholesterol optimum (mild and moderate hypercholesterolemia) for maximally effective functioning of the immunity system.