Levels of soluble adhesion molecules in various clinical presentations of coronary atherosclerosis

Güray, Ümit; Erbay, Ali Rıza; Güray, Yeşım; Yilmaz, Mehmet Birhan; Boyaci, Ayça; Şaşmaz, Hatice; Korkmaz, Şule; Kütük, Emine

doi:10.1016/j.ijcard.2003.07.014

Cited by 84 publications

(59 citation statements)

References 33 publications

(30 reference statements)

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“…Patients with stable CAD have moderately increased and in several studies even normal levels of soluble VCAM 1 in comparison with healthy controls. The highest level of VCAM 1 was noted in patients with acute myocardial infarction [35]. In another study, VCAM 1 was a useful marker for predicting future ischemic events in the 6 months after presentation with unstable angina pectoris or nonQ myocardial infarction [36].…”

Section: G1 (Cvd+ Dlp+/-) G2 (Cvd- Dlp+) G3 (Cvd- Dlp-)mentioning

confidence: 89%

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Novotny¹,

Vaverková²,

Karásek³

2012

Lipoproteins - Role in Health and Diseases

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Section: G1 (Cvd+ Dlp+/-) G2 (Cvd- Dlp+) G3 (Cvd- Dlp-)mentioning

confidence: 89%

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Novotny¹,

Vaverková²,

Karásek³

2012

Lipoproteins - Role in Health and Diseases

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“…17,18 Elevated blood levels of soluble intracellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1) and E-selectin are associated with increased severity of atherosclerosis and risk for myocardial infarction. [19][20][21] Conversely, the adipocyte-derived molecule adiponectin, which appears to have both anti-inflammatory and antiatherogenic properties, has been shown to be lower in obese participants compared to lean controls. 22 This obesity-mediated reduction in adiponectin levels is also inversely related with the upregulation of the adhesion molecules ICAM-1, VCAM-1 and E-selectin.…”

Section: Introductionmentioning

confidence: 99%

Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women

et al. 2007

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Background: Overweight individuals commonly demonstrate elevated levels of inflammatory and cell adhesion molecules. Elevated levels of inflammation and adhesion have been implicated in the pathogenesis of cardiovascular disease. Aerobic exercise has been shown to be effective in altering specific biomarkers of inflammation and cell adhesion; however, little is known regarding the effects of resistance training (RT) on these biomarkers. This study examined the effects of 1 year of moderate-intensity RT on biomarkers of inflammation and adhesion in healthy, overweight women. Methods and Results: Participants included 28 (12 control, 16 RT) overweight (body mass indexX25 kg/m 2 ) women, aged 25-44 years, studied before and after 1 year of RT. C-reactive protein (CRP), interleukin-6 (IL-6), adiponectin, intracellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin were measured by standard enzyme-linked immunosorbent assays. Body composition, blood pressure, fasting blood lipids, glucose and insulin also were assessed. There were no significant changes in blood pressure, fasting blood lipids, glucose or insulin levels in either group after 1 year. There was also no change in body mass or fat mass in either group; however, there was a significant increase in lean body mass (Po0.05) in the RT group. Both CRP (Po0.01) and adiponectin (Po0.01) demonstrated significant improvements in the RT group, with no change in IL-6. Conversely, there were no associated changes in the biomarkers of cell adhesion in either group. Conclusions: This study demonstrates that moderate-intensity RT significantly results in modest improvements of inflammatory markers without affecting cell adhesion molecules in overweight women.

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“…13,22,[26][27][28] It is accentuated that the increase (even a little higher than the average values) of the markers of endothelial dysfunction in healthy individuals is connected to an elevated risk of developing atherosclerosis. 22,[29][30][31] which requires the determination of reliable discriminant values (cut-off) to evaluate …”

Section: Discussionmentioning

confidence: 99%

Is everything clear about Tako-Tsubo syndrome?

Petrov

Tokmakova²,

Marchov³

et al. 2011

Folia Medica

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IntroductIon: tako-tsubo syndrome is a novel cardio-vascular disease affecting predominantly postmenopausal women exposed to unexpected strong emotional or physical stress, in the absence of significant coronary heart disease. It is characterized by acute onset of severe chest pain and/or acute left ventricular failure, eCg-changes, typical left ventricular angiographic findings, good prognosis and positive resolution of the morphological and clinical manifestations. First described in 1990 in Japan by Sato, Tako

show abstract

Levels of soluble adhesion molecules in various clinical presentations of coronary atherosclerosis

Cited by 84 publications

References 33 publications

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Adiponectin: A Perspective Adipose Tissue Marker with Antiinflammatory and Antiaterogenic Potencial

Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women

Is everything clear about Tako-Tsubo syndrome?

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