LEVELS OF “N TERMINAL- PRO BRAIN NATRIURETIC PEPTIDE” (NT-proBNP) AND ASSOCIATED RISK FACTORS IN SYSTOLIC HEART FAILURE CONSEQUENTIAL TO ISCHAEMIC HEART DISEASE

Abstract

BACKGROUND Early identification of Heart Failure as a post MI complication is very important in a clinical setting. Particularly in a resource strapped environment such as a centre in a remote district. Our study aims to study levels of NT-pro BNP in Systolic Heart Failure consequential to Ischaemic Heart Disease, the correlation between the levels of NT-pro BNP and Systolic Heart Failure consequential to Ischaemic Heart Disease and study the risk factors in patients presenting with Heart Failure consequential to Ischaemic Heart Disease and their correlation to NT-proBNP Levels if any is present. MATERIALS AND METHODS 100 patients admitted into Basaveshwar Teaching and General Hospital Attached to M.R. Medical College diagnosed with Systolic Heart Failure (Ejection Fraction <40%) after Ischaemic Heart Disease. A previously designed proforma was used to collect data on cases admitted complete detailed history and clinical examination was taken and performed NT-PRO BNP, Troponin I, Echocardiography, ECG were performed. The data collected was then made into a chart and subjected to statistical analysis. There was no long term or short term follow up of the patient.

Comparison between the Levels of N Terminal Pro-Brain Natriuretic Peptide and Troponin I to Predict Left Ventricular Ejection Fraction in Patients Presenting with First ST-Elevation Myocardial Infarction

“…13,14 Regarded as one of the cardiovascular markers of both short-and long-term prognosis in patients who present in the setting of acute myocardial infarction it serves an important role for treatment and further management of these patients. 15,16 Studies in the past have shown that in patients presenting with Acute coronary syndrome the Pro BNP levels increased initially reaching a maximum level within forty-eight hours. It has also been documented that the release of BNP starts immediately after AMI event and takes 16 hours to reach peak.…”