“…In the same way, metalinduced oxidative stress seems to play an important role in the etiology of other chronic diseases, such as cardiovascular and respiratory diseases, neurological disorders, etc (Jomova and Valko, 2011). Furthermore, accumulating evidence provides correlations between the exposure to trace elements and various adverse effects, such as those recently found for Ti, Cu, Cd, Rb and altered heart rate variability (Feng et al, 2015), for Cs and Sb and high blood pressure (Shiue and Hristova, 2014), for Ti and Sb and the risk of adverse pregnancy outcomes (Zheng et al, 2014), and for Cd and Mn and cognition and behavior in childhood (Sanders et al, 2015). Additional evidences of detrimental effects for human health, albeit more limited and recovered in occupational scenarios or in very polluted areas, were found also for Ga (Chen, 2007), Li, B, and Sr (Usuda et al, 2007).…”