Abstract:This study was carried out to evaluate the effects of increasing levels of digestible methionine+cystine on performance and carcass composition of high genetic potential barrows for lean deposition. Sixty-four barrows with initial weight of 95.46 ± 1.09 kg were allotted to a completely randomized block design, with four levels of digestible methionine+cystine (0.427, 0.466, 0.504, and 0.545%, corresponding to the digestible methionine+cystine:digestible lysine ratios of 57.0, 62.0, 67.0 and 73.0%, respectively… Show more
“…On the contrary, a Met deficiency in pigs can lead to lower DWG (Conde-Aguilera et al, 2014), growth suppression of the intestinal mucosa, reduction of intestinal epithelium, and increase of oxidative stress (Bauchart-Thevret et al, 2009;Chen et al, 2014). Several studies have showed that pigs can tolerate some Met deficiency (Santos et al, 2011;Ying et al, 2015) or excess levels in the diet (Pena et al, 2008).…”
Section: Discussionmentioning
confidence: 99%
“…Methionine (Met) is the second or thirdlimiting aminoacid (AA) in conventional diets for growing pigs, which can lead to its deficiency, reduced availability for protein synthesis and limited growth (Bauchart-Thevret et al, 2009;NRC, 2012;Chen et al, 2014). The Met levels present in most dietary ingredients for pigs are insufficient; thus, it must be provided from a synthetic source (Santos et al, 2011). Additionally, bioavailability and bioefficacy of synthetic DL-Met isomers show inconsistent results in growth performance of pigs (Shen et al, 2014;Kong et al, 2016).…”
Section: Introductionmentioning
confidence: 99%
“…(Opapeju et al, 2012;de Oliveira et al, 2015). Although pigs can tolerate some shortage or surplus of Met (Pena et al, 2008;Santos et al, 2011;Ying et al, 2015) its excess can affect growth performance and carcass characteristics, while low Met levels can increase fat deposition, reducing protein synthesis (Conde-Aguilera et al, 2014). Appropriate dietary concentration of Met depends on each analyzed variable (Zhang et al, 2013).…”
Background: Methionine (Met) requirements have not been clearly established for fattening pigs due to their metabolic interrelationships and its bioavailability for protein synthesis. Objective: To determine the optimum level of regular crystalline or protected Met in pig diets from nursery to finishing. Methods: A total of 48 crossbred pigs (11.74±1.72 kg of initial body weight) were used. The treatments consisted of adding four levels (0.00, 0.05, 0.10, 0.15% in addition to dietary content) and two types of Met (regular and protected) to pig diets. Results: Nursery, Finishing I, and II pigs fed protected Met increased daily feed intake (DFI; p≤0.10). Protected Met raised daily weight gain (DWG) in nursery pigs and increased backfat thickness (BT) in nursery and grower pigs (p≤0.10). In Finishing I pigs, protected Met increased DWG and improved carcass characteristics (p≤0.10). In nursery and grower pigs, an extra 0.15% Met decreased feed:gain ratio (FGR; p≤0.10). In grower and Finishing II pigs fed extra 0.05% Met improved DWG and extra 0.10% Met reduced plasma urea concentration (p≤0.10). Conclusions: Feeding protected Met in pig diets increases DWG, DFI and BT. Increasing 0.05-0.15% Met level improves FGR, DWG, potentially reducing nitrogen excretion to the environment.
“…On the contrary, a Met deficiency in pigs can lead to lower DWG (Conde-Aguilera et al, 2014), growth suppression of the intestinal mucosa, reduction of intestinal epithelium, and increase of oxidative stress (Bauchart-Thevret et al, 2009;Chen et al, 2014). Several studies have showed that pigs can tolerate some Met deficiency (Santos et al, 2011;Ying et al, 2015) or excess levels in the diet (Pena et al, 2008).…”
Section: Discussionmentioning
confidence: 99%
“…Methionine (Met) is the second or thirdlimiting aminoacid (AA) in conventional diets for growing pigs, which can lead to its deficiency, reduced availability for protein synthesis and limited growth (Bauchart-Thevret et al, 2009;NRC, 2012;Chen et al, 2014). The Met levels present in most dietary ingredients for pigs are insufficient; thus, it must be provided from a synthetic source (Santos et al, 2011). Additionally, bioavailability and bioefficacy of synthetic DL-Met isomers show inconsistent results in growth performance of pigs (Shen et al, 2014;Kong et al, 2016).…”
Section: Introductionmentioning
confidence: 99%
“…(Opapeju et al, 2012;de Oliveira et al, 2015). Although pigs can tolerate some shortage or surplus of Met (Pena et al, 2008;Santos et al, 2011;Ying et al, 2015) its excess can affect growth performance and carcass characteristics, while low Met levels can increase fat deposition, reducing protein synthesis (Conde-Aguilera et al, 2014). Appropriate dietary concentration of Met depends on each analyzed variable (Zhang et al, 2013).…”
Background: Methionine (Met) requirements have not been clearly established for fattening pigs due to their metabolic interrelationships and its bioavailability for protein synthesis. Objective: To determine the optimum level of regular crystalline or protected Met in pig diets from nursery to finishing. Methods: A total of 48 crossbred pigs (11.74±1.72 kg of initial body weight) were used. The treatments consisted of adding four levels (0.00, 0.05, 0.10, 0.15% in addition to dietary content) and two types of Met (regular and protected) to pig diets. Results: Nursery, Finishing I, and II pigs fed protected Met increased daily feed intake (DFI; p≤0.10). Protected Met raised daily weight gain (DWG) in nursery pigs and increased backfat thickness (BT) in nursery and grower pigs (p≤0.10). In Finishing I pigs, protected Met increased DWG and improved carcass characteristics (p≤0.10). In nursery and grower pigs, an extra 0.15% Met decreased feed:gain ratio (FGR; p≤0.10). In grower and Finishing II pigs fed extra 0.05% Met improved DWG and extra 0.10% Met reduced plasma urea concentration (p≤0.10). Conclusions: Feeding protected Met in pig diets increases DWG, DFI and BT. Increasing 0.05-0.15% Met level improves FGR, DWG, potentially reducing nitrogen excretion to the environment.
“…In addition potassium citrate is usually taken as a drug for reducing renal acidosis [99]. In food, animal proteins containing methionine like meat break down into cystines which increase urinary cystine level in the body [100]. In a study it was shown that urinary cysteine excretion reduced to 34% by consuming very low protein diet nearly 20g/day [101].…”
Food intake plays a pivotal role of human growth, which necessarily contributes 45% of global economy and wellbeing in general. Consumption of balanced food is elementary for overall good health while a shift of equilibrium can lead to malnutrition, prenatal death, obesity, osteoporosis and bone fractures, coronary heart diseases (CHD), idiopathic hypercalciuria, diabetes and many more. Though CHD, osteoporosis, malnutrition, obesity are being classified thoroughly in the literature, there are fragmented findings in the regime of kidney stone diseases (KSD) and the correlation with food intake therein. KSD associated with hematuria and renal failure poses an increasing threat to the healthcare and global economy while its emergence of Indian populations is being affected with multi-factorial urological disorder resulting from several factors. In this realm, epidemiological, biochemical, macroeconomic situations been portrayed when food intake is also a paramount importance which rarely been forecasted. Hence, in this article we will be reviewing the corollary connotation with diverse food consumption and the efficacy it plays in KSD extrapolating in Indian context.
“…Cysteine (Cys) is included in the structure of many proteins, linking polypeptide chains as a precursor of taurine and glutathione (Baker, 1991). Most Cys must be obtained from dietary Met since many feed ingredients lack of adequate Cys levels (Santos et al, 2011). Thus, Met should be added into pig diets to meet the methionine+cysteine (Met+Cys) complex requirement.…”
Background: The addition of synthetic methionine to growing pig diets should consider the requirements of the methionine+cysteine complex, as most cysteine is obtained through dietary methionine. Objective: To determine an optimal level of methionine+cysteine (Met+Cys) in growing pig diets. Methods: Ninety-nine hybrid (Yorkshire×Landrace×Duroc) barrows were used in a completely randomized design (initial body weight: 25.90±3.99 kg). Nine levels of Met+Cys (0.500, 0.525, 0.550, 0.575, 0.600, 0.625, 0.650, 0.675, and 0.700%) were evaluated during 35 days. To determine a multi-objective optimal level of Met+Cys, growth performance and strongly related carcass traits were evaluated. Results: Average daily feed intake (ADFI) and feed:gain ratio (FGR) showed a linear response to the dietary Met+Cys level (p<0.05), with estimated optimal concentration at 0.700%. Average daily gain (ADG) did not show any effect on the Met+Cys level (p>0.05). Carcass characteristics were not affected by the Met+Cys concentration (p>0.05). The multi-objective optimal level for ADG, ADFI, and FGR was 0.667% Met+Cys. Conclusions: According to our results, 0.667% Met+Cys is the best concentration in diets for growing pigs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.