Background and Purpose. Cardiac rehabilitation has been shown to be effective in people with chronic heart failure (CHF), particularly in terms of exercise capacity. However, no effects have been found on the level of movement-related everyday activity. Therefore, rehabilitation programs also should focus on enhancing the level of movementrelated everyday activity. The aim of this study was to explore factors associated with the level of movement-related everyday activity and with quality of life in people with CHF. Subjects and Methods. Measurements of movement-related everyday activity (using an accelerometrybased Activity Monitor), quality of life, and associated factors were performed in 36 people with stable CHF (New York Heart Association classes II and III). Results. Knee flexion and extension torque, and particularly extension torque, were significantly associated with movement-related everyday activity (r ϭ.43-.49, PϽ.05), whereas nonphysiological factors such as feelings of being disabled were associated with quality of life PՅ.01, PϽ.05). No relationship was found between movement-related everyday activity and quality of life PϾ.05). Discussion and Conclusion. The results indicate that knee torque is associated with the level of movement-related everyday activity in people with CHF and that quality of life is mediated by nonphysiological factors. [van den Berg-Emons RJ, Bussmann JB, Balk AH, Stam HJ. Factors associated with the level of movementrelated everyday activity and quality of life in people with chronic heart failure. Phys Ther. 2005;85:1340 -1348 Key Words: Determinant, Everyday activity, Fitness, Heart failure, Quality of life. P eople with chronic heart failure (CHF) may be restricted in the performance of normal everyday activities such as walking, housekeeping, gardening, and shopping. As a result, we believe that they may experience diminished function due to a sequence of negative effects: hypoactivity leading to reduced fitness, leading to further hypoactivity. In a previous study, 1 we found that the mean duration that people with CHF performed movement-related activities during a day was considerably lower compared with subjects who were healthy (0.8 versus 2.2 hours per day, respectively; PϽ.05). This hypoactivity in CHF also has been found in other studies [2][3][4][5][6] and may have detrimental effects on fitness, 6 social participation, and prognosis. 7 Furthermore, considerable reductions in several areas of quality of life have been reported in people with CHF. 8,9 It may be hypothesized that this decreased quality of life is partly caused by hypoactivity. 10,11 Cardiac rehabilitation in people with CHF has been shown to be effective, particularly in terms of exercise capacity 12-15 and quality of life. 9,16 However, increased exercise capacity does not necessarily result in a more active lifestyle (eg, more or longer periods of walking or cycling in everyday life). In our randomized clinical trial in people with CHF, 6 in which an experimental group participated in a ...