Levamisole on the biochemical and hematological responses to parasitism by monogenoids in dog snapper

Abstract

The response of biochemical and hematological parameters were analyzed in dog snapper (Lutjanus jocu) grown in net cages, as well as for the specimens kept in the laboratory during an infestation by Neobenedenia melleni, and after treatment with freshwater bath and injectable application of levamisole. Significant changes were observed in N. melleni parasitized individuals, characterized by increased glucose and lactate levels, as well as a significant fish hematocrit reduction and leukocyte increase. Treatment with freshwater baths, concomitant with injectable levamisole application, showed therapeutic efficacy in several parameters after 14 days of treatment.

Safety of the anthelminthic drugs levamisole, fenbendazole, and ivermectin administered in therapeutic baths for the common carp Cyprinus carpio

“…The increase in the blood GLU and LACT concentrations demonstrates a response to metabolic stress (Wendelaar Bonga 1997). Our findings agree with those of Pahor-Filho et al (2017), Oliveira et al (2019a), Oliveira et al (2019b), andSadati et al (2021) who also detected an increase in the glucose or lactate concentration in Serrasalmidae (pacu, dog snapper) and beluga (Huso huso) following an LHC treatment. In contrast, an LHC treatment was reported not to affect the glucose concentration in tambaqui (da Silva et al 2021) and juvenile pacu (Sado et al 2010).…”