Leukotriene E4 and Endothelin-1 Levels, Their Response to the Therapy, Potential Relationship with Gastroesophageal Reflux and Developing of Infantile Asthma in Wheezy Infants
Abstract:A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Wheezing is a common symptom among children and is proposed to be associated with inflammatory cell infiltration, cytokines production, and with some risk factors such as gastro esophageal reflux (GER). The aim of the present study was to investigate endotheline-1 (ET-1) and leukotriene-E4 (LTE-4) levels, their response to steroid and β2-agonist therapy, and to establish if these parameters can be used as a diagnostic tool for infantile asthma and assess… Show more
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