Leukemoid Reaction to Mumps Virus

Mumps—an Uncommon Cause of Lymphocytic Leukaemoid Reaction and Thrombocytopenic Purpura

“…mm., with both an absolute and a relative lymphocytosis (6, 7). However, the cases recorded here present an unusual and atypical leucocyte response and they differ from the one reported by Garcia and Rasch (1) in which there was no associated thrombocytopenia.…”

“…A leukaemoid reaction to mumps virus infection has been recorded only once (1). Thrombocytopenic purpura is also an uncommon complication of mumps.…”

Mumps

“…These include arthritis in adults/5.17.46.112.11B) with an incidence of 0.44% among 1334 patients during an outbreak in Paris in 1923--1924.07) Viruria is common in mumps infection, and this may be accompanied by abnormal renal function tests/" 9l and rarely by nephritis,l4.64.86.96) which is sometimes fatal. (4,64) Hematological complications are rare but include a leukemoid reaction (42) and paroxysmal cold hemoglobinuria. (24) No evidence of a relationship to leukemia was found in children of mothers who had mumps during preg-nancyY) Holowach et al (63) described a case of congenital chorioretinitis in a 6-month-old infant whose mother had been infected by mumps in the latter part of the first trimester, and these authors feel on review of the literature that mumps infection at this time could affect the fetus.…”