“…The finding that mitochondria are subject to significant negative changes during leucosis transformation in PSHC and bone marrow hemato- and lympho-poiesis precursor cells agrees with our assumption. For instance, according to well-established information [ 7 , 8 ], these changes are mainly qualitative in patients with acute lymphoblast leukemia (ALL) and acute myeloid leukemia (AML), and consist in the following: the number of irregular-shaped mitochondria grows, the mitochondrial matrix and membranes are damaged, cristae are disorganized, etc. By these indicators, leucosis cells do not differ from neoplastic cells of other types.…”