Leukemia: Oddities in Onset and Course

Childhood leukaemia presenting in the central nervous system.

“…Davies and Owor (1965) have pointed out the high incidence of chloroma and other solid reticuloendothelial tumours in East African children, some of which enter a leukaemic phase; and Cavdar et al (1971) and Mortada (1962Mortada ( , 1968 have drawn attention to the frequency of myelomonocytic leukaemia presenting in this way in Egyptian children. Of the 7 cases reported of diffuse intracerebral involvement at diagnosis (Creskoff, 1953;Lusher, 1964;Kwaan, Pierre, and Long, 1969;Hurwitz, Sutherland, and Walker, 1970;Porter, 1970;Borgstedt et al, 1970), only one was subsequently shown to have lymphoblastic leukaemia (Levine, Winkelstein, and Shadduck, 1973).…”