Leucocyte Groups and Histocompatibility

Rood, Jon J. van

doi:10.1111/j.1423-0410.1966.tb04603.x

“…PD is the second most common degenerative disease of the CNS, affecting 1% of the population above 60 years (Tysnes and Storstein 2017). PD is characterized by the degeneration of the dopaminergic neurons (DAn) in the substantia nigra pars compacta (SNpc), causing the characteristic motor factors of PD like rigidity, bradykinesia, tremors, and postural instability, along with other nonmotor symptoms.…”

Section: Neurodegenerative Diseasesmentioning

confidence: 99%

Stem Cell Therapy

Graffmann¹,

Spitzhorn²,

Martins³

et al. 2020

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

0

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Stem cell therapy and regenerative medicine have a tremendous potential for the treatment of a wide variety of currently fatal diseases. So far, routine stem cell based therapies are limited to the treatment of hematologic and dermatologic malignancies, but the field is continuously evolving. One research focus lies on mesenchymal stem cells (MSCs) which have an immunomodulatory potential and support regenerative processes throughout the body. Pluripotent stem cells, on the other hand, can be differentiated into every cell type and might be able to replace damaged tissue in the future. Currently, stem cell based clinical trials are ongoing for a broad range of diseases affecting every organ, and the number of

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“…PD is the second most common degenerative disease of the CNS, affecting 1% of the population above 60 years (Tysnes and Storstein 2017). PD is characterized by the degeneration of the dopaminergic neurons (DAn) in the substantia nigra pars compacta (SNpc), causing the characteristic motor factors of PD like rigidity, bradykinesia, tremors, and postural instability, along with other non-motor symptoms.…”

Section: Neurodegenerative Diseasesmentioning

confidence: 99%

Stem Cell Therapy

Graffmann¹,

Spitzhorn²,

Martins³

et al. 2019

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

1

0

View full text Add to dashboard Cite

Stem cell therapy and regenerative medicine have a tremendous potential for the treatment of a wide variety of currently fatal diseases. So far, routine stem cell based therapies are limited to the treatment of hematologic and dermatologic malignancies, but the field is continuously evolving. One research focus lies on mesenchymal stem cells (MSCs) which have an immunomodulatory potential and support regenerative processes throughout the body. Pluripotent stem cells, on the other hand, can be differentiated into every cell type and might be able to replace damaged tissue in the future. Currently, stem cell based clinical trials are ongoing for a broad range of diseases affecting every organ, and the number of therapies that are obtaining approval, at least in

show abstract