Leucemia and pregnancy

Leukaemia and Pregnancy

“…From the data they produced it is not possible to check this figure or to state the percentage for stillbirths or prematurity. Excluding the 41 cases of their review, and one abortion and one caesarean section reported by Williams (1948), of the remaining 15 cases of non-interrupted pregnancies, there were 3 stillborn, 3 premature (including twins of Case 4), and 10 live children. The foetal mortality rate is therefore 37.5%, and stillbirths and prematurity are each responsible for 50% of the mortality.…”

“…Taussig (1936) states that in acute leukaemia there is little to be gained by termination of pregnancy and that it is hardly, if ever, justified, except in terminal cases in which the possibility of securing a viable child presents itself. Williams (1948) employed caesarean section in one case of chronic and one case of acute leukaemia with survival of the mothers and offspring. McGoldrick and Lapp came to the conclusion that most cases stand parturition well, only to collapse shortly afterwards, but that in many cases the course of the leukaemia is not greatly, if at all, affected by pregnancy.…”

“…Chronic Ieukaemia accounted for 45 cases-42 myelogenous and 3 lymphogenous. Williams (1948) traced eight additional cases and described two cases personally known to him, one of which was of acute monocytic type and which was claimed by him to be the only instance of this variety recorded. His series included three cases of acute leukaemia one lymphatic, one myeloid, and one monocytic-and seven cases of chronic myeloid type; whilst Li et al (1947) recorded four cases of the chronic myeloid variety.…”

“…McGoldrick and Lapp (1943) McGoldrick and Lapp's review (1943) .. Williams (1948) .. Williams' review (1948) . .…”

Monocytic Leukaemia and Pulmonary Tuberculosis Complicating Pregnancy

“…In view of its rarity the following case is considered worthy of record. Williams (1948) first reported a case of acute monocytic leukaemia and pregnancy, the patient (aged 35) dying within 12 days of caesarean section. Two cases of monocytic leukaemia and active tuberculosis have been reported (Heller and Hiles, 1946).…”