LETTERS TO THE EDITOR: Postoperative pericardial effusion in patients receiving anticoagulants for deep vein thrombosis after coronary artery bypass graft surgery

Ambrosetti, Marco; Ageno, Walter; Salerno, Mario; Pedretti, Roberto F.E.

doi:10.1111/j.1538-7836.2005.01575.x

Cited by 3 publications

(5 citation statements)

References 4 publications

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“…Similar to bleeding after cardiac surgery, therapeutic systemic anticoagulation (INR >2.5) was the only reported risk factor for cardiac tamponade after valvular surgery in another observational study not included in this review 85. No multivariate analysis on risk factors for cardiac tamponade or pericardial effusion was, however, presented in these studies 27, 75, 76, 85…”

Section: Resultsmentioning

confidence: 94%

“…The majority of the studies were observational studies (n=49), 16 studies were RCTs, and 3 were meta‐analyses (Tables 1 and 2). 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84 Of the 16 RCTs identified,1...…”

Section: Resultsmentioning

confidence: 99%

“…75 Similarly, initiation of systemic anticoagulation for confirmed VTE also did not increase the risk of pericardial effusion in patients who took aspirin after CABG surgery. 27 Similar to bleeding after cardiac surgery, therapeutic systemic anticoagulation (INR >2.5) was the only reported risk factor for cardiac tamponade after valvular surgery in another observational study not included in this review. 85 No multivariate analysis on risk factors for cardiac tamponade or pericardial effusion was, however, presented in these studies.…”

Section: Incidences and Risk Factors For Complications From Vte Prophmentioning

confidence: 90%

“…85 No multivariate analysis on risk factors for cardiac tamponade or pericardial effusion was, however, presented in these studies. 27,75,76,85…”

Section: Incidences and Risk Factors For Complications From Vte Prophmentioning

confidence: 99%

See 3 more Smart Citations

Incidence of Venous Thromboembolism and Benefits and Risks of Thromboprophylaxis After Cardiac Surgery: A Systematic Review and Meta‐Analysis

Bham

Pavey

2015

JAHA

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BackgroundOptimal thromboprophylaxis after cardiac surgery is uncertain. This systematic review aimed to define the incidence and risk factors for deep vein thrombosis (DVT), fatal and nonfatal pulmonary embolism (PE), and assess whether venous thromboembolism (VTE) prophylaxis was effective in reducing VTE without complications after cardiac surgery.Methods and ResultsTwo reviewers independently searched and assessed the quality and outcomes of randomized, controlled trials (RCTs) and observational studies on VTE after cardiac surgery in the MEDLINE, EMBASE, and Cochrane controlled trial register (1966 to December 2014). Sixty‐eight studies provided data on VTE outcomes or complications related to thromboprophylaxis after cardiac surgery. The majority of the studies were observational studies (n=49), 16 studies were RCTs, and 3 were meta‐analyses. VTE prophylaxis was associated with a reduced risk of PE (relative risk [RR], 0.45; 95% confidence interval [CI], 0.28–0.72; P=0.0008) or symptomatic VTE (RR, 0.44; 95% CI, 0.28–0.71; P=0.0006) compared to the control without significant heterogeneity. Median incidence (interquartile range) of symptomatic DVT, PE, and fatal PE were 3.2% (0.6–8.1), 0.6% (0.3–2.9), and 0.3% (0.08–1.7), respectively. Previous history of VTE, obesity, left or right ventricular failure, and prolonged bed rest, mechanical ventilation, or use of a central venous catheter were common risk factors for VTE. Bleeding or cardiac tamponade requiring reoperation owing to pharmacological VTE prophylaxis alone, without systemic anticoagulation, was not observed.ConclusionsUnless proven otherwise by adequately powered RCTs, initiating pharmacological VTE prophylaxis as soon as possible after cardiac surgery for patients who have no active bleeding is highly recommended.

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Section: Resultsmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Section: Incidences and Risk Factors For Complications From Vte Prophmentioning

confidence: 90%

“…85 No multivariate analysis on risk factors for cardiac tamponade or pericardial effusion was, however, presented in these studies. 27,75,76,85…”

Section: Incidences and Risk Factors For Complications From Vte Prophmentioning

confidence: 99%

See 2 more Smart Citations

Incidence of Venous Thromboembolism and Benefits and Risks of Thromboprophylaxis After Cardiac Surgery: A Systematic Review and Meta‐Analysis

Bham

Pavey

2015

JAHA

View full text Add to dashboard Cite

show abstract

“…15,20 -22 a. Elastic graduated compression stockings (GCS), such as T.E.D. 24,25 Several published guidelines recommend routine use of unfractionated heparin (UFH) 5000 units SC bid starting the day after surgery with use of a more intensive regimen (enoxaparin 40 mg qd or 30 mg bid) in patients at higher risk. b.…”

Section: Preventionmentioning

confidence: 99%