Letters

Rahimi-Movaghar,; Ar, Vaccaro

doi:10.1097/brs.0b013e3181adb789

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Chronic low back pain may require surgical management. Among the surgical approaches, lumbar discectomy is a common procedure that consists of partially removing an intervertebral disc compressing the nerve root or spinal cord [55]. However, this procedure is associated with high levels of postoperative pain, which results in increased length of hospital stay and impacts on public health systems.…”

Section: Pain After Lumbar Discectomymentioning

confidence: 99%

Methylene Blue for the Treatment of Health Conditions: a Scoping Review

Galvan

Borsoi

Julek

et al. 2021

Braz. arch. biol. technol.

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studies evaluating effective drugs for health conditions are of crucial importance for public health. Methylene blue (MB) is an accessible synthetic drug that presents low toxicity and has been used in several health areas due to its effectiveness. Objective: this scoping review aims to provide a comprehensive overview of relevant research regarding the use of MB for the treatment of health conditions. Methods: a fivestage framework Arksey and O'maley scoping review was conducted. The literature was searched in Cochrane Library database using Mesh term "methylene blue". Data were collected by two independent reviewers and submitted to descriptive synthesis. Results: The search resulted in 429 records, from which 16 were included after exclusion criteria were applied. The therapeutic use of MB was identified for acute conditions (malaria and septic shock), chronic conditions (discogenic back pain, bipolar disorder, refractory neuropathic pain, and post-traumatic stress disorder), and postoperative care (vasoplegic syndrome, and pain after haemorrhoidectomy, lumbar discectomy, and traumatic thoracolumbar fixation). Conclusion: there is much evidence emerging from clinical trials about the therapeutic use of MB for acute, chronic, and HIGHLIGHTS  This scoping review summarizes the findings of clinical trials using methylene blue (MB) for the treatment of various health conditions.  This research method allowed mapping main findings, clarifying research topics, and identifying gaps in the literature.

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Section: Pain After Lumbar Discectomymentioning

confidence: 99%