Letter: would aspirin alleviate fibrosis in alcoholic liver disease?

Letter: hepatitis B surface seroclearance does reduce the risk of hepatocellular carcinoma

“…This is extremely high as compared with 1-14.3% ever reported in the literatures, 3,9 including that in their own previous study (17.7%). 10 Perhaps old age at HBsAg seroclearance and high proportion of viremia after HBsAg seroclearance might increase the HCC development in the study by Gounder's et al 1 More information is needed for a valid discussion.…”

“…SIRS, We read with great interest the nested case-control study by Gounder et al 1 The study included 238 case patients and 435 control patients with sex, genotype and age-matched at cohort entry, and concluded that hepatitis B surface antigen (HBsAg) seroclearance was not associated with reduced risk of hepatocellular carcinoma (HCC) development. This is contradictory to observations of previous studies that HCC could occur at a lower rate after HBsAg seroclearance.…”