Letter to the Editor

Kuzumoto, Yoshimasa; Shioyama, Mitsuaki; Kihara, Mikihiro; Kusunoki, Susumu

doi:10.1002/mus.20538

Cited by 6 publications

(1 citation statement)

References 6 publications

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“…showed an association between autonomic test abnormality and anti-GQ1b antibody in MFS. 8 Recent studies on GBS indicate that these complications are not only limited to severely disabled patients who require mechanical ventilation, but also affect those with milder forms of the condition, who do not require artificial ventilation and are able to walk more than 5 meters. 2 , 3 The degree of motor impairment could not predict the occurrence of serious bradyarrythmias, including sinus arrest.…”

Section: Discussionmentioning

confidence: 99%

Miller Fisher syndrome with sinus arrest

et al. 2017

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Dysautonomia in Guillain-Barre syndrome (GBS) rarely causes serious cardiovascular complications, such as sinus arrest. Miller Fisher syndrome (MFS) is recognized as a variant of GBS. There have been few reports regarding the association between MFS and dysautonomia. We describe a case of a 68-year-old man with ophthalmoplegia, bulbar palsy, truncal ataxia, and areflexia. He was diagnosed with MFS because he exhibited the classical clinical triad and had elevated serum anti- GQ1b immunoglobulin G levels. A magnetic resonance imaging scan of his head was normal. His 24-hour Holter recording showed sinus arrest. He was treated with intravenous immunoglobulin, whereupon his symptoms gradually improved. This included the sinus arrest, which was considered a symptom of dysautonomia in MFS. Therefore, clinicians should be mindful of dysautonomia not only in GBS patients, but also in cases of MFS.

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Section: Discussionmentioning

confidence: 99%