Letter to the editor: Trends in tuberculosis notification rates by country of origin in the metropolitan area of Rome, 2010 to 2015

Schepisi, Monica Sañé; Scognamiglio, Paola; D'Amato, M; Girardi, Enrico; Puro, Vincenzo

doi:10.2807/1560-7917.es.2017.22.27.30570

Cited by 2 publications

(2 citation statements)

References 4 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, Italy has become in recent years one of the main refugee entry points to Europe, and the conditions in the shelter centers and the complexity of management of migrants in highly populated metropolitan areas, where most of the asylum-seekers converge, can increase the probability of tuberculosis transmission 9. As other metropolitan cities in western Europe, Rome and the surrounding area host an ethnically heterogeneous population, well represented by individuals migrating from countries with a high incidence of the disease, leading to TB rates of 10.5/100,000 cases, much higher than those found in Italy as a whole 10. As stated by WHO in its latest report on TB in the European region, migrants to countries with a low incidence of TB have been shown to be at increased risk of MDR-TB compared with the host population, suggesting that testing and treatment for drug-resistant TB in all individuals diagnosed with TB should be part of a basic package of care 11,12.…”

Section: Introductionmentioning

confidence: 99%

<p>Multidrug-Resistant Tuberculosis In A Referral Center In Rome: 2011– 2016</p>

Cannas

Butera

Gualano

et al. 2019

IDR

View full text Add to dashboard Cite

PurposeMultidrug-resistant tuberculosis (MDR-TB) is a major burden to public health in low incidence countries in Europe. The aim of this study was to attempt to have a better insight into the trends of MDR-TB in the metropolitan area of Rome, within the Italian and the foreign-born population, based on microbiological and demographic data.Patients and methodsWe performed a prospective study, collecting microbiological data based on phenotypic drug-resistant testing (DST) of TB strains consecutively isolated in a referral hospital in Rome, the capital city of a low TB incidence country, over a 6-year period, and correlated them to the geographical origin of patients. This study was carried out in a referral hospital for patients with drug-resistant TB from the whole region.ResultsDrug-resistance data from 926 patients with a microbiological diagnosis of TB from 2011 to 2016 show a 5.5% rate of MDR-TB, mostly occurring in patients born in a single East European country, that has a high incidence of MDR-TB. The strains isolated from these patients frequently carry additional resistances, leading to an increased risk of developing extensively drug-resistant (XDR) TB.ConclusionIn the great metropolitan area of Rome, MDR-TB more frequently occurs in patients who were born in a single country from Eastern Europe known to have high rates of MDR-TB and long-time residents in Italy. Recent immigrants from non-European countries do not appear to contribute to the rates of MDR-TB reported in this article. This knowledge of local TB trends could help improve the measures of surveillance and prevention of disease.

show abstract

Section: Introductionmentioning

confidence: 99%

<p>Multidrug-Resistant Tuberculosis In A Referral Center In Rome: 2011– 2016</p>

Cannas

Butera

Gualano

et al. 2019

IDR

View full text Add to dashboard Cite

show abstract

“…Although the risk posed by migrants with TB to autochthonous populations seems low, they contribute disproportionately to the national TB burden in low TB incidence countries [ 3 ]. In these countries, TB incidence is generally declining, although at the current pace the achievement of the pre-elimination threshold (defined as less than 1 case per 100.000 inhabitants) will not be possible without specific interventions that address the needs of migrant populations [ 4 – 6 ].…”

Section: Introductionmentioning

confidence: 99%

Socioeconomic status and biomedical risk factors in migrants and native tuberculosis patients in Italy

et al. 2017

Self Cite

View full text Add to dashboard Cite

Action on social determinants is a main component of the World Health Organization End Tuberculosis (TB) Strategy. The aim of the study was to collect information on socioeconomic characteristics and biomedical risk factors in migrant TB patients in Italy and compare it with data collected among Italian TB patients. A cross-sectional study was conducted among TB patients aged ≥18 years over a 12-months enrolment period in 12 major Italian hospitals. Information on education, employment, housing and income was collected, and European Union Statistics on Income and Living Conditions index was used to assess material deprivation. Among migrants, we also analyzed factors associated with severe material deprivation. Migrants were compared with younger (18–64 years) and older (65+ years) Italians patients. Out of 755 patients enrolled (with a median age of 42 years, interquartile range: 31–53), 65% were migrants. Pulmonary, microbiologically confirmed, and new cases were 80%, 73%, and 87% respectively. Prevalence of co-morbidities (i.e. diabetes, chronic kidney disease, neoplastic diseases and use of immunosuppressive drugs) was lower among migrants compared to Italian TB patients, while indicators of socioeconomic status, income and housing conditions were worst in migrants. Forty-six percent of migrants were severely deprived vs. 9% of Italians (p<0.0001, 11.3% and 5.5% among younger and older Italians, respectively). Among migrants, being male, older, irregular, unemployed, with a shorter time spent in Italy, a lower education level, and without a co-morbidity diagnosis were factors associated with severe material deprivation at multi-variable logistic regression. Moreover, socioeconomic indicators for Italian patients did not differ from those reported for the general Italian population, while migrant TB patients seem to have a higher prevalence of severe material deprivation than other migrants residing in Italy. Intervention to address the needs of this population are urgent.

show abstract

Letter to the editor: Trends in tuberculosis notification rates by country of origin in the metropolitan area of Rome, 2010 to 2015

Cited by 2 publications

References 4 publications

<p>Multidrug-Resistant Tuberculosis In A Referral Center In Rome: 2011– 2016</p>

<p>Multidrug-Resistant Tuberculosis In A Referral Center In Rome: 2011– 2016</p>

Socioeconomic status and biomedical risk factors in migrants and native tuberculosis patients in Italy

Contact Info

Product

Resources

About