Letter to the Editor : Are Prescribing Indicators Essentially Representing the Frail Older Population?

Abstract

To the Editor: Older populations have multiple comorbidchronic diseases that require multiple treatments, which makethem the larger consumer of medications (1). As a persongrows older the ability to tolerate medications become poor dueto age-related changes in pharmacokinetics andpharmacodynamics. The number of comorbidities increaseswith age that leads to the increase in number of medicationprescribed which is associated with increased risk of adversedrug events (ADEs), impaired mobility, morbidity,hospitalization and death.