“…Fernandez-Banares and Gisbert on our article. 1,2 We agree that our definition of budesonide dependence was broad, namely recurrence of diarrhoea after budesonide discontinuation. We also agree with their clinically important recommendation that maintenance budesonide should be used at the lowest effective dose, to minimise the risk of steroid-related side effects and cost, as noted in reviews from the USA and Europe.…”