Letter: tenofovir disoproxil fumarate is safe for prevention of mother‐to‐child transmission of hepatitis B virus

Abstract

Linked ContentThis article is linked to Wang et al and Pan and Zhang papers. To view these articles, visit https://doi.org/10.1111/apt.15064 and https://doi.org/10.1111/apt.15382.

Letter: tenofovir disoproxil fumarate is safe for prevention of mother‐to‐child transmission of hepatitis B virus. Authors’ reply

“…We read with great interest the meta-analysis by Grigg et al, 1 1. The principle of meta-analysis does not allow for combining effect estimates from various study designs.…”

“…Authors' reply EDITORS, Dr Fan et al commented on the safety data in our study and presented a meta-analysis involving 624 mothers on TDF. 1,2 Their positive comments are much appreciated. Although they indicated the need to further reveal the maternal and foetal safety of TDF in realworld studies, their meta-analysis data were largely extracted from three RCTs (n = 316 on TDF), [3][4][5] which may not necessarily represent patients in the real-world setting.…”