Letter: Metoclopramide and facial dyskinesia.

Abstract

is poor and on the verge of disintegration. The key figures in the service, the consultants, are being treated like serfs and the whole setup is reminiscent of a sinking ship. Moreover, the salary for tihese proposed coordinators was to be a consultant's starting salary. How could one offer less? A first-year full-time consultant like myself would find that the nine-to-five office worker was drawing the same salary with no clinical responsibility and the vaguest of notions of job description. Many of the applicants did not even know what the job enitailed. One

Serum dopamine beta hydroxylase activity and metoclopramide provocative test in torsion dystonia

“…This activity is responsable for the antiemetic and gastrointestinal regulating effect and stimulation of lactation. Of 34 published cases with extrapyramidal effects, 30 cases had head and neck dystonia [2,3,4,5,6,7,8] (Table 1). Because of this we used MP as a provocative test in families with torsion dystonia (TD).…”

“…In these three cases the serum DBH activity doubled and tripled. It is suggested that the MP induced elevation of serum DBH activity in relatives of TD patients indicates a genetic disposition.Metoclopramide (MP) occasionally leads to extrapyramidal effects comprising dystonia of the head and neck [1,2,3,4,5,6,7,8]. MP is a procainamide derivative (Fig.…”

The synaptic significance of metoclopramide induced dyskinetic-dystonic head and neck movements in pregnancy

“…Together with the increased use of metoclopramide (MP) as a therapeutic tool in medicine and as a diagnostic tool [21,22,25,27,30,37,38,46, 50] a great number of cases with extrapyramidal side effects such as dyskinesias has been reported [7,8,12,23,32,36,44,47,59]. These reports come mainly from the old continent.…”

Current Psychopathological Theories of Tardive Dyskinesia and Their Implications for Future Research

“…Yamadori and Alpert [18] have reported TD after methyldopa (aldomet) ad ministration, which abated upon discontin uation of the medication. Similarly, metoclopramide, a drug used widely for the relief of upper gastrointestinal symptoms, has been reported to produce acute facial dyskinesia [19] and dystonia [20,21] indicating its po tential in producing TD. In fact, Lavy et al [22] have reported the occurrence of TD in a 48-year-old female following prolonged ad ministration of this drug.…”