2016
DOI: 10.1161/strokeaha.116.012755
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Letter by Terao et al Regarding Article, “Damage to the Left Precentral Gyrus Is Associated With Apraxia of Speech in Acute Stroke”

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Cited by 4 publications
(5 citation statements)
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“…This suggests that recovery of motor speech planning, which is lateralized to the left hemisphere [8], depends, at least partially, on the function of contralesional homologue areas. Our findings are also in line with results obtained in healthy subjects, showing that motor speech production, although lateralized towards the dominant hemisphere, relies on motor cortical networks of both hemispheres [2]. Regarding the future of AOS therapy, our results further suggest that inhibition of contralesional homologue areas should probably be avoided.…”
supporting
confidence: 91%
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“…This suggests that recovery of motor speech planning, which is lateralized to the left hemisphere [8], depends, at least partially, on the function of contralesional homologue areas. Our findings are also in line with results obtained in healthy subjects, showing that motor speech production, although lateralized towards the dominant hemisphere, relies on motor cortical networks of both hemispheres [2]. Regarding the future of AOS therapy, our results further suggest that inhibition of contralesional homologue areas should probably be avoided.…”
supporting
confidence: 91%
“…AOS is most often accompanied by aphasia, whereas isolated forms may rarely occur after focal damage to the left precentral gyrus [1]. How AOS recovers after brain damage is poorly understood [2]. In particular, it is not known whether recovery of AOS solely depends on the functional reorganisation of perilesional areas [3,4], or whether it also depends on the compensation through contralesional homologue areas.…”
mentioning
confidence: 99%
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“…PLD3 has been reported to be involved in myogenesis [451]. PLD4 is described not to have phospholipase D catalytic activity [665], but has been associated with inflammatory disorders [447,574,593]. Sequence analysis suggests that PLD5 is catalytically inactive.…”
Section: Commentsmentioning
confidence: 99%
“…PLD3 has been reported to be involved in myogenesis [522]. PLD4 is described not to have phospholipase D catalytic activity [765], but has been associated with inflammatory disorders [518,659,679]. Sequence analysis suggests that PLD5 is catalytically inactive.…”
Section: Further Reading Onmentioning
confidence: 99%