Letrozole administration effects on the P450aromatase expression and the reproductive parameters in male sheep (Ovis aries)
Antônio Francisco da Silva Lisboa Neto,
Túlio Teruo Yoshinaga,
Antonio de Sousa Júnior
et al.
Abstract:Letrozole comprises a non-steroid aromatase inhibitor that has been applied as a preventive for many uses, such as breast cancer prevention, treatment of hormonal dysfunction, and male infertility. Precisely in Northeast Brazil, ovine consist of the leading livestock produced, and their reproduction in captivity has been demonstrated difficult. Thus, we hypothesized whether the application of letrozole will improve male sheep reproduction. One group of 6 animals received a daily dosage of 0.5mg/Kg of letrozole… Show more
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