Lessons learned using an MRI-only workflow during high-dose-rate brachytherapy for prostate cancer

Murgić, Jure; Chung, Peter; Berlin, Alejandro; Bayley, Andrew; Warde, Padraig; Catton, Charles; Simeonov, Anna; Abed, Jessy; O’Leary, Gerald; Rink, Alexandra; Ménard, Cynthia

doi:10.1016/j.brachy.2015.12.004

Cited by 29 publications

(23 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For these reasons, some centers have adopted MRI-based needle insertion (22, 23, 25, 42) or MRI-based planning of HDR prostate implants (22, 23, 25), sacrificing workflow efficiency in the hopes of improving accuracy. This approach has been shown to be feasible at several specialty centers, with overall procedure times approaching 4-5 hours.…”

Section: Resultsmentioning

confidence: 99%

“…More importantly however, is that with MRI, tumors can be visualized and delineated in most patients with intermediate- or high-risk disease (23). This improves confidence in tumor coverage during planning, especially in the small subset of patients with extraprostatic extension of disease.…”

Section: Resultsmentioning

confidence: 99%

“…However dedicated MRI in brachytherapy operating rooms are unlikely to be widely available in the near future. Potential solutions include performing the implantation in a diagnostic MRI suite to avoid the need to move the patient for image acquisition (23), or performing the MRI and the treatment on the MRI couch, avoiding the need to transfer the patient to another couch once the imaging process is complete. These alternative necessitate the use of MRI-compatible equipment and specific processes, which may be feasible in tertiary centers, but the overall procedure time in two prospective studies was shown to be 4-5 hours (22, 23).…”

Section: Discussionmentioning

confidence: 99%

“…Assuming there is a clinical benefit, adding serial MRI and prolonging operating room time would add costs that would need to be justified by improved clinical outcomes, especially knowing that the main driver of costs in prostate brachytherapy is the time spent in the operating room (48). The procedure duration has been shown to follow a learning curve and to decrease over time, leading to a decrease in operating room costs (22, 23). For LDR brachytherapy, it is possible to reduce the costs by using the diagnostic MRI instead of obtaining an additional scan and to omit the day 30 scan if the day 0 dosimetry is satisfactory.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Clinical use of magnetic resonance imaging across the prostate brachytherapy workflow

2017

View full text Add to dashboard Cite

Magnetic resonance imaging (MRI) produces better soft tissue contrast than does ultrasonography (US) or computed tomography (CT) for visualizing male pelvic anatomy and prostate cancer. Better visualization of the tumor and organs at risk could allow better conformation of the dose to the target volumes while at the same time minimizing the dose to critical structures and the associated toxicity. Although the use of MRI for prostate brachytherapy would theoretically result in an improved therapeutic ratio, its implementation been slow, mostly because of technical challenges. In this review we describe the potential role of MRI at different steps in the treatment workflow for prostate brachytherapy: for patient selection, treatment planning, in the operating room, or for post-implant assessment. We further present the current clinical experience with MRI-guided prostate brachytherapy, both for permanent seed implantation and high-dose-rate brachytherapy.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical use of magnetic resonance imaging across the prostate brachytherapy workflow

2017

View full text Add to dashboard Cite

show abstract

“…71 Brachytherapy is characterized by a steep dose fall off with increas- 72 ing distance to the radioactive source. The dose fall off is approximately 73 proportional to 1/r 2 , where r is the distance to the source [1]. Typical 74 dose gradients at the border of a target are as high as 5-20% per mm.…”

Section: Image Guided Therapymentioning

confidence: 98%

Advancements in brachytherapy

Tanderup

Ménard

Polgár

et al. 2017

Advanced Drug Delivery Reviews

Self Cite

View full text Add to dashboard Cite

Deep learning in MRI‐guided radiation therapy: A systematic review

Eidex,

Ding,

Wang

et al. 2023

J Applied Clin Med Phys

View full text Add to dashboard Cite

Recent advances in MRI‐guided radiation therapy (MRgRT) and deep learning techniques encourage fully adaptive radiation therapy (ART), real‐time MRI monitoring, and the MRI‐only treatment planning workflow. Given the rapid growth and emergence of new state‐of‐the‐art methods in these fields, we systematically review 197 studies written on or before December 31, 2022, and categorize the studies into the areas of image segmentation, image synthesis, radiomics, and real time MRI. Building from the underlying deep learning methods, we discuss their clinical importance and current challenges in facilitating small tumor segmentation, accurate x‐ray attenuation information from MRI, tumor characterization and prognosis, and tumor motion tracking. In particular, we highlight the recent trends in deep learning such as the emergence of multi‐modal, visual transformer, and diffusion models.

show abstract

Lessons learned using an MRI-only workflow during high-dose-rate brachytherapy for prostate cancer

Cited by 29 publications

References 31 publications

Clinical use of magnetic resonance imaging across the prostate brachytherapy workflow

Clinical use of magnetic resonance imaging across the prostate brachytherapy workflow

Advancements in brachytherapy

Deep learning in MRI‐guided radiation therapy: A systematic review

Contact Info

Product

Resources

About