Lessons Learned From Yet Another Episode of Diethylene Glycol Poisoning

Brent, Jeffrey

doi:10.1001/jamainternmed.2014.19

Cited by 7 publications

(1 citation statement)

References 6 publications

(11 reference statements)

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“…In 1995, a report of fatal diethylene glycol poisoning following the administration of contaminated paracetamol syrup to children emerged from Bangladesh [1]. This case echoed similar incidents in the late 1930s in the United States, contemporaneously in Nigeria, and subsequently in other countries, most recently in February 2020 in India [2][3][4][5][6]. In 2017, the World Health Organization (WHO) estimated the global prevalence of Substandard and Falsified (SF) medicines at 10.5% based on data from mostly Low-and Middle-Income Countries (LMICs).…”

Section: Introductionmentioning

confidence: 93%

The integrity of the antimicrobial supply chain in Bangladesh: assessing the regulatory environment and contextual challenges

Orubu

Samad

Rahman

et al. 2022

J Public Health Pol

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Most low-and middle-income countries lack the regulatory capacity to contain substandard and falsified (SF) medicines. Innovations for strengthening regulatory systems are needed to protect public health. We assessed the integrity of the antimicrobial supply chain in Bangladesh. We employed qualitative methods comprising policy content analysis, and literature and database reviews. Using a framework modified from the World Health Organization's and the United States Pharmacopoeia's, the Bangladesh National Drug Policy (BNDP), was evaluated for provisions on medicines quality assurance mechanisms. We used newspaper, peer-reviewed, and post-marketing surveillance reports to assess prevalence of SF antimicrobials. The BNDP contains provisions for quality assurance. Newspaper reports identified circulation of substandard antimicrobials. We identified only six peer-review studies testing antimicrobial product quality with three studies reporting out-of-specifications products. We suggest three strategies for strengthening the regulatory system: community-based surveillance, task shifting, and technology-enabled consumer participation.

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