Less invasive ventricular enhancement (LIVE) as potential therapy for ischaemic cardiomyopathy end-stage heart failure

Abstract

Background: Surgical ventricular reshaping (SVR) is a treatment option for patients with severe ischaemic heart failure (HF). Recently, a new minimally invasive, hybrid technique named "less invasive ventricular enhancement" (LIVE), has been developed adopting the Reviven™ Myocardial Anchoring System

Safety and efficacy of less-invasive ventricular enhancement procedure with the transcatheter Revivent TCTM system in patients with left ventricular aneurysm: a systematic review

“…Similar results were reported in another study with a smaller population [10]. Loforte et al observed that LV reconstruction was associated with a reduction in LV volumes and LVEF (P = 0.001).…”

“…[8][9][10][11][12]). All studies [8][9][10][11][12] had an observational, non-randomized design, and three of them were performed in multiple centers [8,9,12]. Also, two studies enrolled patients prospectively [9,11].…”

“…Also, two studies enrolled patients prospectively [9,11]. As this hybrid procedure was addressed to a specific population, all patients included in clinical studies had a history of MI and a reduced LVEF, ≤35% [10,12], <40% [8,11] or ≤45% but >15% [9]. Almost all studies included patients with NYHA class II-IV [8,9,11,12] and with LVESVI >60 mL/m 2 [9][10][11][12].…”

“…Results and outcomes reported in clinical studies included in the present systematic review were illustrated in Table 2 (Ref. [8][9][10][11][12]).…”

“…The new hybrid intervention, LIVE procedure, using a percutaneous approach and a left minithoracotomy, emerged as a therapeutic option for LV aneurysm exclusion. Significantly, patients with high surgical risk could benefit from this procedure as it is performed without induced cardioplegia, cardiopulmonary bypass circuit, and ventriculotomy [10,12].…”