Lesions of the Clitoris

Heller, Debra S.

doi:10.1097/lgt.0000000000000028

Cited by 6 publications

(2 citation statements)

References 73 publications

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“…The main objective of the treatment was local tumor reduction and metastatic occurrence prevention. The chemotherapy regimens, generally included a combination of effective agents, such as cyclophosphamide, Case Reports in Obstetrics and Gynecology actinomycin D, cisplatin, carboplatin, vincristine, and etopo- [10,11,14,16,17]. Our case showed a significant efficiency of this chemotherapy regimen with significant decrease of the tumor size after only 3 weeks of treatment (Figure 3).…”

Section: Discussionmentioning

confidence: 63%

About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review

Mian

Loue

Koui

2023

Case Reports in Obstetrics and Gynecology

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Background. Rhabdomyosarcoma (RMS) is a rare high-grade malignant tumor and the most common soft-tissue sarcoma, which occurs in young girl over 5 years old. Multimodality treatment associating with surgery, chemotherapy, and/or radiotherapy culminate in a >70% overall 5-year survival. This is the first case reported in 30 years of practice in Côte d’Ivoire, low- and middle-income country (LMIC). Objective. To summarize clinical data, the significant alternative chemotherapy efficiency and difficulties related to the prognosis evaluation in an LMIC. Case. A 2-year-old girl had been examined for a large mass in the vulvar region and clitoris. We carried out a biopsy for histopathologist exam. This allows pathologic, genetic, and biological characterization of nonmetastatic botryoid rhabdomyosarcoma. A multidisciplinary team decision of neoadjuvant chemotherapy was retained combining vincristine, cyclophosphamide, and actinomycin D or alternatively with Adriamycin. After 3 weeks of chemotherapy, significant volumetric reduction of tumor was observed. Yet a surgical removal was proposed but not performed because the patient has no longer consulted our medical center and was lost to follow-up. Therefore, we cannot assess the long-term evolution and prognosis. Conclusion. Embryonal RMS (ERMS) of clitoris is a rare malignant tumor of infant. Histology and immunohistochemistry are essential for diagnostic but unavailable in our context. We want to emphasize on the difficulties encountered in treatment and prognosis assessment. The primary free surgical removal of the vulva with adjuvant chemotherapy and/or radiotherapy must then be implemented in our practice.

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Section: Discussionmentioning

confidence: 63%

About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review

Mian

Loue

Koui

2023

Case Reports in Obstetrics and Gynecology

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“…Der Pilonidalsinus tritt vornehmlich in der Rima ani auf, wird aber auch im Nabelbereich [106,170,175,247,316], inter-und submammillär [422], an Vulva, Mons pubis und Klitoris, [212,213,239], Penis [268,350], Anus [365,452], interdigital (z. B. bei Friseuren; [57,168,376,447]), an der Fingerspitze [198] im Bereich der Brust [176] und auch im Bereich der Nase [238] und hinter den Ohren gesehen [485].…”

Section: Lokalisationunclassified

S3-Leitlinie: Sinus pilonidalis. 2. revidierte Fassung 2020

2020

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Beteiligte Fachgesellschaften Deutsche Gesellschaft für Koloproktologie (DGK); federführend Deutsche Gesellschaft für Allgemein-und Viszeralchirurgie (DGAV) Chirurgische Arbeitsgemeinschaft für Coloproktologie (CACP) Berufsverband der Coloproktologen Deutschlands (BCD) Deutsche Gesellschaft für Gastroenterologie, Verdauungs-und Stoffwechselkrankheiten (DGVS) Deutsche Dermatologische Gesellschaft (DDG) 1. Einleitung und Definition Der Pilonidalsinus oder Sinus pilonidalis (pilus = Haar, nidus = Nest) ist eine akut oder chronisch verlaufende Entzündung im subkutanen Fettgewebe, überwiegend im Bereich der Steißbeinregion.

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Diseases of the Vulva and Anal Neoplasia

Heller

2015

OB-GYN Pathology for the Clinician

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Lesions of the Clitoris

Abstract: The clitoris may become involved by vulvar lesions. There are also lesions arising from the clitoris. A familiarity with these lesions is necessary for the high index of suspicion needed for their diagnosis.

Cited by 6 publications

References 73 publications

About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review

About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review

S3-Leitlinie: Sinus pilonidalis. 2. revidierte Fassung 2020

Diseases of the Vulva and Anal Neoplasia

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