Lesions Observed in Accessory Spleens of 311 Patients

Halpert, Béla; Györkey, Ferenc

doi:10.1093/ajcp/32.2.165

Cited by 252 publications

(274 citation statements)

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“…1,9,10 CT is an imaging technique commonly used to evaluate gastrointestinal tract diseases including SMT, 11,12 and is useful in making a differential diagnosis of an accessory spleen. 2,10 Accessory spleens appear round or oval, and the attenuation is identical to that of normal splenic parenchyma both before and after administration of contrast medium in CT, 2,10 as observed in the present patient. EUS is a better modality than CT for differentiating between an SMT and an extrinsic compression lesion of stomach.…”

Section: Discussionsupporting

confidence: 79%

“…Accessory spleens can appear as an abdominal mass in post-splenectomy CT. 1 They have been observed in 10-31% of autopsy cases and may manifest as solitary or multiple lesions. 2,3 While accessory spleens have been found at sites from the diaphragm to the scrotum, the vast majority are located in the spleen region, usually in the splenic hilum or along the splenic vessels or associated ligaments.…”

Section: Introductionmentioning

confidence: 99%

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Diagnosis of an Accessory Spleen Mimicking a Gastric Submucosal Tumor Using Endoscopic Ultrasonography-guided Fine-needle Aspiration

Ahn

Jung

Kim

et al. 2012

Korean J Gastroenterol

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Accessory spleen can be mistaken as a gastric subepithelial mass, and may not be differentiated in CT or endoscopic ultrasonography (EUS). A gastric subepithelial mass was detected on routine endoscopy in a 39-year old woman with history of splenectomy. In subsequent CT and EUS, the subepithelial mass was located on the fourth layer of the stomach. To make a definite diagnosis, EUS-guided fine needle aspiration (FNA) was performed, and a splenic tissue was demonstrated in histologic examination. EUS-guided FNA can be beneficial in the diagnosis of accessory spleen which mimics a gastric subepithelial mass. (Korean J Gastroenterol 2012;59:433-436)

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Section: Discussionsupporting

confidence: 79%

Section: Introductionmentioning

confidence: 99%

Diagnosis of an Accessory Spleen Mimicking a Gastric Submucosal Tumor Using Endoscopic Ultrasonography-guided Fine-needle Aspiration

Ahn

Jung

Kim

et al. 2012

Korean J Gastroenterol

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“…the other hand, when there is no history of trauma, another explanation is a developmental disorder around the 5th week of gestation, in which isolated splenic cells are shed from the spleen to the pancreas (5) . Autopsy studies revealed abdominal splenosis in 10%-30% of the patients (5,10) . In other study in which 1,000 patients underwent CT, abdominal accessory spleen was found in 16% of the patients (20) .…”

Section: Discussionmentioning

confidence: 98%

“…In 80% of these cases, accessory spleen was located near the splenic hilum. The second most common site was the tail of the pancreas (17%) (10) . In our series, PS was found in 0.6% of the patients with pancreatic nodules submitted to EUS-FNA.…”

Section: Discussionmentioning

confidence: 99%

Pancreatic Splenosis Mimicking Neuroendocrine Tumors:

Ardengh¹,

Lopes

Kemp

et al. 2013

Arq. Gastroenterol.

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-Context -Pancreatic splenosis is a benign condition which can mimic a pancreatic neoplasm. Objective -To describe the role of the endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of pancreatic nodules suspicious for pancreatic splenosis. Method -From 1997 to 2011, patients with pancreatic solid tumors suspicious for splenosis by computed tomography and/or magnetic resonance imaging were referred to EUS-FNA. Those cases with pancreatic splenosis confirmed by EUS-FNA or surgery were included. Endosonographic findings and clinicopathologic features were also analysed. Results -A total of 2,060 patients with pancreatic solid tumors underwent EUS-FNA. Fourteen (0.6%) cases with pancreatic splenosis were found. After applying exclusion criteria, 11 patients were selected. Most patients were male (7), young (mean age: 42 years) and asymptomatic (8). Endoscopic ultrasound imaging alone suspected pancreatic splenosis in 6 cases, and neuroendocrine tumors in 5 cases. Pancreatic splenosis was found most commonly in the tail, was round, hypoechoic, with homogeneous pattern, regular borders, and with scintigraphy negative for somatostatin receptors. The average diameter of these nodules identified by endoscopic ultrasound was 2.15 cm. Microhistology obtained by EUS-FNA confirmed the diagnosis in 9/10 patients. Conclusion -Pancreatic splenosis can be diagnosed by EUS-FNA. Microhistology prevents unnecessary surgeries, and reassures asymptomatic patients with hypoechoic, homogeneous, and well circumscribed pancreatic nodules.

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“…It may also result from an extreme lobulation of the spleen pinching off splenic tissue (2). It is present in 15.6% of patients undergoing abdominal CT (4) and is found during 10% of autopsy series (5,6). The accessory spleen is most often localized in or near the splenic hilum (80%) and the second most common location (16.8%) is the area of the pancreatic tail (5).…”

mentioning

confidence: 99%