Lesions experimentally produced by fungi implicated in extrinsic allergic alveolitis

Abstract

The ability of Aureobasidium pullulans, Cladosporium herbarum and Cryptostroma corticale to produce local lesions in the rabbit was examined. Both C. corticale and A. pullulans can survive in vivo and produce the inflammatory response typical of mycetoma. C. herbarum failed to grow or survive in vivo.

Cutaneous infection of a porcupine (Erethizon dorsatum) byAureobasidium pullulans

“…pullulans has induced experimental infections in laboratory animals (Akagi et al, t958;Vermeil et al, 1971 ;Bulman & Stretton, 1974;Nakazima, 1957) and formed symbiotic associations with various insect groups (Cooke, 1959), but the present isolation of A. pullulans from a cutaneous infection of a porcupine (Erethizon dorsatum) is the first reported association of this microorganism with natural infection 0feither a wild or domesticated animal.…”

Drought Stress Can Induce the Pathogenicity of Cryptostroma corticale, the Causal Agent of Sooty Bark Disease of Sycamore Maple

“…The growth of C. corticale stopped at 35 • C on PDA plates. Nevertheless, Bulman and Stretton [31] showed that C. corticale can survive and grow slowly at 37 • C in an experimental animal (rabbit). However, Emanuel, Wenzel, and Lawton [30] stated that C. corticale did not grow at 37 • C. The maximum temperature for C. corticale in maple wood is difficult to extrapolate from the mentioned experiments and thus need to be addressed in future studies.…”

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Pullulan PI-20 for use as a new food additive

“…The fungus is also reported to be a frequent source of respiratory allergy (Kurup et al, 2000) and IgE antibodies to Aureobasidium pullulans have been identified in sera from individuals with suspected mould allergy (Karlsson-Borga et al, 1989). Experimentally it has been demonstrated to cause extrinsic allergic alveolitis in the rabbit (Bulman, 1974).…”