Lésions endométriale et endocervicale associées au pseudomyxome péritonéal : à propos d’une observation

Samet, Ines; Cormier, B.; Mowlawi, Hameid; Philippe, Anne; Arbion, Flavie; Fetissof, F

doi:10.1016/j.annpat.2009.02.017

Cited by 8 publications

(5 citation statements)

References 15 publications

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“…Therefore, this case further establishes the capacity of appendiceal primary neoplasia to colonize the endometrial surface (presumably via transit through the fallopian tubes), as both acellular mucin and neoplastic mucinous epithelium have previously rarely been observed to involve the endometrial surface in the context of an appendiceal mucinous neoplasm with pseudomyxoma peritonei [9–11]. …”

Section: Discussionmentioning

confidence: 72%

Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge

Vavinskaya

Baumgartner

et al. 2016

Case Reports in Obstetrics and Gynecology

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Primary appendiceal mucinous lesions are uncommon and represent a spectrum from nonneoplastic mucous retention cysts to invasive adenocarcinoma. Low-grade appendiceal mucinous neoplasms (LAMNs) represent an intermediate category on this spectrum and can be classified according to whether or not they are confined to the appendix. Although LAMNs are frequently confined to the appendix, they can also spread to the peritoneum and clinically progress as pseudomyxoma peritonei (i.e., mucinous ascites). Thus, the appropriate classification of appendiceal primary neoplasia is essential for prognosis and influences clinical management. In addition, the precise classification, management, and clinical outcome of patients with disseminated peritoneal disease remain controversial. Here, we report an unusual case of LAMN with pseudomyxoma peritonei that initially presented with mucinous and bloody vaginal discharge. Pathological evaluation revealed low-grade appendiceal mucinous neoplasm with secondary involvement of the peritoneum, ovaries, and endometrial surface. Therefore, LAMN should be considered in the differential diagnosis of mucinous vaginal discharge.

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Section: Discussionmentioning

confidence: 72%

Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge

Vavinskaya

Baumgartner

et al. 2016

Case Reports in Obstetrics and Gynecology

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“…Retrograde transtubal migration of tumour cells with subsequent peritoneal implantation occurs in endometrial serous carcinomas . However, anterograde implantation of peritoneal or ovarian tumours is less well documented, although it is known that pseudomyxoma peritonei of appendiceal origin can involve the endometrium and cervix . Nonetheless, in this case, the possibility of multicentricity cannot be excluded, especially as the ependymoma patterns were strikingly different in the ovarian tumour (solid or pseudoglandular) and the endometrial tumour (pure papillary architecture).…”

Section: Introductionmentioning

confidence: 76%

Papillary ependymoma of the endometrium

Schuldt

Retamero

Bergeron³

et al. 2014

Histopathology

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Pathogenetically, the presence of this uterine ependymoma could represent either an example of multicentricity or a phenomenon of transtubal implantation of the ovarian tumour. Exceptionally, papillary ependymoma can occur in the endometrium, and may prompt differential diagnoses with other papillary endometrial tumours. Pathologists should consider this rare possibility in the differential diagnosis of papillary ovarian and endometrial lesions.

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“…And the immunohistochemistry phenotype of the primary and secondary lesion was consistent, displaying the expression of intestinal type marker (CDX2,CK20) rather than primary endometrium neoplasia inmunophenotype [4][5][6][7][8]. Appendiceal mucinous neoplasm involving the endometrium exhibiting gastric-type differentiation is not reported in previous literatures.…”

Section: Discussionmentioning

confidence: 96%

“…Regarding the growth pattern of appendix mucinous tumors involving the ovary, a spectrum of benign metaplastic to maligant mucinous lesions can be observed [9]. This ability of colonization native epithelium may lead to neoplasm extension [4,5,7,8]. In our study, the spectrum of benign gastric-type metaplasia to atypical proliferation(boderline) in the uterus poly is observed, suggesting benign endometrial mucinous metaplasia of extrauterus tumor involvement have the equal potential of progression to borderline or even malignant, mimicking primary endometrial cancer.…”

Section: Discussionmentioning

confidence: 99%

Appendiceal Adenocarcinoma Involving the Uterus and Mimicking Primary Endometrial Atypical Gastric-Type Mucinous Proliferation : A Rare Case Report

Min

Xiang

Liang

et al. 2022

Preprint

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Gastric/gastrointestinal-type mucious lesion in the endometrium may be mostly primary or cervix gastric-type adenocarcinoma involvement. Gastriointestinal and pancreatobiliary adenocarcinoma involving the endometrium is rare. We report a rare appendiceal adenocarcinoma of a 55-year-old female, involving the uterus, mimicking primary endometrial gastric-type lesion. Endometrial lesion was associated with a polyp, which was composed of significant complex papillary architecture and crowed glands resembling lobular endocervical glandular hyperplasia (LEGH), with cytologically abundant pale eosinophilic cytoplasm and atypical nuclear. Mucinous epithelium cells of endometrial lesion was diffusely positive for MUC6, CK7 and negative for p16, PAX8, ER, NapsinA. This histologic morphology and immunophenotype show gastric-type differentiation. Meanwhile, the appendiceal tumor exhibited conventional intestinal type manifestation but focal invasive adenocarcinoma with abundant pale eosinophilic cytoplasm and focally immunoreactivity for MUC6. On the basis of morphologic and immunoreativity examination of the endometrial and appendix, We believe that the diagnosis of atypical mucinous proliferation of gastric-type of endometrium arising from appendiceal adenocarcinoma can be established. Patient died of disease at 3 months after surgery.

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Lésions endométriale et endocervicale associées au pseudomyxome péritonéal : à propos d’une observation

Cited by 8 publications

References 15 publications

Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge

Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge

Papillary ependymoma of the endometrium

Appendiceal Adenocarcinoma Involving the Uterus and Mimicking Primary Endometrial Atypical Gastric-Type Mucinous Proliferation : A Rare Case Report

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