Lesiones pernióticas y acrales en España durante el confinamiento por COVID: análisis retrospectivo de 12 casos

Foot Manifestations in a COVID-19–Positive Patient: A Case Study

“…It is being published immediately due to the timely nature of the topic. 6 Limitations of this case study include a lack of a biopsy, additional lab investigations, and radiographs to discover if bone changes occurred. Also lacking in this study is any type of clinical gait analysis to examine the progression of the changes in the patient's gait and the precise description of the gait alteration.…”

Acral purpuric lesions (erythema multiforme type) associated with thrombotic vasculopathy in a child during the COVID‐19 pandemic

“…Dermal oedema, vacuolar alteration of the basal layer, necrotic keratinocytes and mixed infiltrate with a mainly perivascular and perieccrine distribution in the superficial and deep dermis and the hypodermis have been notified. [2][3][4] However, our histological findings are reminiscent of the pauci-inflammatory thrombogenic vasculopathy that occurs seriously ill hospitalized COVID-19 patients with COVID-19. This thrombogenic vasculopathy is due to activation of the complement pathways and an associated procoagulant state.…”

“…To the Editor Recently, young COVID-19 patients have presented with erythematous and purpuric acral lesions similar to chilblains. [1][2][3] Despite the scarcity of published cases, this topic has attracted significant mass media attention. 4 Dermatologists have noted that more people than would be expected at this time of year are seeking medical attention for these chilblain-like lesions.…”

“…Some have suggested that people presenting with this manifestation should be tested and isolated. 2 Determining the accuracy of this association is, therefore, crucial.…”

“…This clinical and histopathological study reports on the second type of clinical presentation, associated with a thrombotic vasculopathy in the histological study, a finding that has not been reported in asymptomatic patients during the COVID-19 pandemic. 2 A 12-year-old boy who, during the period of COVID-19 lockdown, presented with a pruriginous, haemorrhagic purpuric eruption and vesicular blisters on the heels of both feet, which had developed over a period of 4 days ( Fig. 1) The patient had not taken any new medications and neither he nor his family presented with respiratory symptoms.…”