Lesion- and vessel-specific coronary artery calcium scores are superior to whole-heart Agatston and volume scores in the diagnosis of obstructive coronary artery disease

Correlations Between Aortic Root Calcification and Coronary Artery Atherosclerotic Markers Assessed Using Multidetector Computed Tomography

“…Interestingly, several recent studies have reported that the pattern and progression of calcification in individual coronary arteries are more valuable compared to total heart calcium measurements for risk stratification and prediction of adverse cardiovascular outcomes (20,21). An additional finding of the present study was the observed significant correlation between high ARC and coronary calcified plaques.…”

Coronary Artery Calcium

“…The increased sensitivity and NPV values of the 0.5-mm reconstruction will give physicians more confidence in ruling out CAD and potentially improve the diagnostic accuracy in daily clinical practice. Second, some studies (27,28) have suggested that the geometric measurements of individual calcified lesions are superior to conventional CAC score in predicting vessel stenosis and cardiac events. Thinner reconstruction could entail a higher resolution of the image and a finer geometric measurement of calcified lesions, and therefore, may potentially expand the current clinical paradigm of CAC.…”

Coronary Arterial Calcium and Outcomes

“…Although CAC scoring was initially developed to identify subjects at risk for cardiovascular events, interest has emerged in using calcium scoring for the prediction of obstructive coronary artery disease (CAD). Recent data suggest that lesion-specific and vessel-specific CAC scores improve the predictive accuracy of CAC for obstructive CAD, as compared to the Agatston method [26].…”