Les tumeurs du système nerveux central au Cameroun : histopathologie, démographie

Eyenga, Victor-Claude; Ngah, Joseph Eloundou; Atangana, R.; Etom, Empime; Ngowe, M Ngowe; Bassong, Yves; Oyono, Jean-Louis Essame; Sosso, Maurice Aurélien

doi:10.1684/san.2008.0096

Cited by 9 publications

(8 citation statements)

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“…WHO grade I were the most common histological subtype in our series. Eyenga et al and Mwangombe et al [9,12] found similar findings. Other studies reported astrocytomas to be more frequent [10,13].…”

Section: Histological Types Of Brain Tumorsmentioning

confidence: 56%

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Epidemiological profile of brain tumors in Cameroon: a retrospective study

Motah

Massi

Bekolo

et al. 2021

Egypt J Neurol Psychiatry Neurosurg

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Background Brain tumors represent group of neoplasms originating from intracranial tissues and the meninges. The aim of this study was to determine the epidemiological profile of brain tumors seen in a referral health center in Cameroon. We carried out a 10-year retrospective study in the neurosurgical, neurology, pathology, oncology and radiotherapy units of our hospital. Results We found 150 complete case files accounting for 0.7% of total admissions in the various units. Males accounted for 50.7% of the cases. Children less than 14 years represented 12.7% of cases (n = 19). Primary brain tumors constituted 92% (n = 138). Most patients with primary brain tumors were between 25 and 54 years of age, making up 57% of cases (n = 79). The most prevalent histological type of brain tumor was meningioma (26%, n = 39), followed by astrocytoma (24.7%, n = 37), and pituitary adenomas (18%, n = 27). The majority of cases presented with signs of raised intracranial pressure with headache being the most frequent symptom (88%). Some patients presented with seizures (34%), neurological deficit (13%), visual disturbances (10%), and cognitive disorders (7%). Conclusion Young adults represent the most affected age group. Meningioma, astrocytoma and pituitary adenomas were the most frequent brain tumors in adults. Further studies are needed to assess the long-term outcome of patients with BTs.

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Section: Histological Types Of Brain Tumorsmentioning

confidence: 56%

“…In Cameroon, limited studies have been carried out on BTs. Eyenga et al reported 231 cases of CNS tumors between 1996 and 2006 including 173 (74.9%) BTs [9]. The estimated the annual BTs incidence in Cameroon from 2006 to 2010 was 8 per 100,000 with a male:female ratio of 1:1.5.…”

Section: Introductionmentioning

confidence: 98%

Epidemiological profile of brain tumors in Cameroon: a retrospective study

Motah

Massi

Bekolo

et al. 2021

Egypt J Neurol Psychiatry Neurosurg

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“…We excluded participants who fulfilled the WHO definition of stroke, but had preceding fever or recent weight loss when CT scan results were not available to confirm the diagnosis. Such cases in the study setting where the prevalence of HIV is very high are more likely to be patients with brain abscess (toxoplasmosis) or metastatic tumors, which have been reported to account for about 2% of admission in specialized units in the study setting [22] . While our approach has likely excluded a few patients with true stroke, this was likely the best compromise for an acceptable specificity.…”

Section: Discussionmentioning

confidence: 98%

Computed tomography scanning and stroke mortality in an urban medical unit in Cameroon

et al. 2016

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BackgroundDespite the increasing availability of head computerized tomography (CT) in resource-limited settings, it is unclear if brain-imaging-based diagnosis of stroke affects the outcomes in the absence of dedicated structures for acute stroke management.ObjectivesIn a major referral hospital in the capital city of Cameroon, we compared in-hospital mortality rates in patients with a WHO-based diagnosis of stroke between participants with and without brain imaging on admission.MethodsStroke patients with and without admission brain imaging were compared for demographic characteristics, risk factors, clinical and laboratory characteristic, and in-hospital mortality. Heterogeneities in mortality rates (CT vs. No CT) across major subgroups were investigated via interaction tests, and logistic regressions used to adjust for extraneous factors such as age, sex, year of study, residency, history of diabetes and hypertension, history of stroke, Glasgow coma scale, and delay between stroke symptoms onset and hospital admission.ResultsOf the 1688 participants included in the final analysis, 1048 (62.1%) had brain imaging. The median age of the non-CT vs. CT groups was 65 vs. 62 years (p-value < 0.0001%). The death rate of non-CT vs. CT groups was 27.5% vs. 16.4% (p < 0.0001). This difference was mostly similar across major subgroups, and robust to the adjustments for confounders (in spite of substantial attenuation), with excess deaths in those with CT ranging from 65% to 149%.ConclusionIn this resource-limited environment, the absence of brain imaging on admission was associated with high in-hospital death from stroke, which was only partially explained by delayed hospitalization with severe disease. These results stressed the importance of scaling up acute stroke management in low- and middle-income countries.

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“…The incidence was low in our study (0.07%) over the 10 years of study. In Europe, the incidence of brain tumors was lower in the order of 0.003% but with an average increase of 1.7% per year between 1978 and 1997, partially explained by improved diagnostic capabilities without any variation in risk factors being excluded [11]. Nevertheless, a study carried out in Cameroon on central nervous system tumors showed that the pediatric population represented 15% of the population [12,13].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic and Therapeutic Management of Brain Tumors of Child in Dakar CHU

Thiongane¹

2017

OAJNN

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Introduction: Brain tumors constitute a set of intracranial neoplasms. Their symptomatology associates an intracranial hypertension syndrome (HTIC) and focal neurological syndrome. The objective of our work was to study diagnostic and therapeutic management of brain tumors in children hospitalized at the National Hospital for Children Albert Royer (CHNEAR) in Dakar. Materials and methods:This was a retrospective study of brain tumors (1 st January 2005 to 31st December 2014). Data were collected from patients and hospital records.Results: Of the 30 patients with brain tumors, only 16 cases were included in our study. The incidence was 0.07%, the age ranged from 3 years to 14 years with an average age of 7.6 ± 3.7 years. The majority of children were under 10 years of age in 75% of the cases. The sex ratio is 2.2 (68% boys and 32% girls). All children were presented with headache, vomiting in 56.3% of cases and visual impairment in 37.5% of cases. Other clinical signs are disorders of alertness, amblyopia and convulsions. Neurological examination found papillary edema in 4 patients, hypertonia in 38%, pyramidal syndrome in 31% of cases, cerebellar syndrome in 37.5% of cases, and meningeal syndrome in 25% of cases. There were 69% of infra tentorial location and 31% in the fourth ventricle. The histological types suspected on cerebral tomodensitometry are ependymoma (18.75%), medulloblastoma (12.5%), astrocytoma (12.5%), Glioblastoma (12.5%) and craniopharyngioma (6.25%). Some patients required preoperative medical treatment (analgesic and neuro-resuscitation). The surgical treatment consisted of a ventriculo-peritoneal derivation in 4 cases, a tumoral excision in 2 cases. Mortality was high in 10 cases (62.5%). Conclusion:Cerebral tumors of the child are relatively frequent. Mortality however remains high.

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Les tumeurs du système nerveux central au Cameroun : histopathologie, démographie

Cited by 9 publications

References 0 publications

Epidemiological profile of brain tumors in Cameroon: a retrospective study

Epidemiological profile of brain tumors in Cameroon: a retrospective study

Computed tomography scanning and stroke mortality in an urban medical unit in Cameroon

Diagnostic and Therapeutic Management of Brain Tumors of Child in Dakar CHU

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