Les psychoses épileptiques interictales

Toffol, Bertrand de; Adachi, Naoto; Kanemoto, Kousuke; El‐Hage, Wissam; Hingray, Coraline

doi:10.1016/j.encep.2020.04.014

Cited by 5 publications

(3 citation statements)

References 88 publications

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“…Studies have shown a strong link between temporal lobe epilepsy and the cerebral hemisphere in interictal psychosis. 9,10 Accumulating literature showed that all forms of psychosis (chronic, acute, interictal, and postictal) are arguably represented in patients with epilepsy which are not unrelated to the manifestation of hallucinations, aggression, and disorders of thought, to mention but a few. 11,12 Despite the fact that this seizure-induced psychiatry anomaly, particularly post-ictal psychosis is treatable and may be averted if presymptomatic risk factors are considered 13 , it is worrisome that many of the established antipsychotic drugs are not without one adverse effect or the other.…”

Section: Introductionmentioning

confidence: 99%

Modulation of the Indices of Psychosis in Post-Convulsive Status Epilepticus Model: The Role of Proanthocyanidin-Rich Fraction

2022

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Vitis vinifera seed contains high content of flavonoids particularly, proanthocyanidins. Experimental studies have demonstrated the anticonvulsant potency of Proanthocyanidins-Rich Fraction (PRF). However, this study was designed to evaluate the psychotropic activities of PRF in the post-convulsive status epilepticus (CSE). Six groups of juvenile rats were kindled for the seizure; 24 hours later, the survived rats were post-treated intraperitoneally with propylene glycol (PG), 0.1 or with graded doses of PRF (30 mg/kg, 20 mg/kg, or 10 mg/kg body weight [BW]) or diazepam (DZP) (5 mg/kg BW) for a period of one week. Three weeks after the last treatment, both the control and post-convulsed rats were examined for the markers of depression, anxiety, and muricidal actions. they were kept untreated but with access to feed and water for 21 days. There was a significant increase in the markers of anxiety-like behavior, locomotor activities, and depression-related behavior in the post-CSE rats compared with the control. The post-CSE rats exhibited impairment in societal interaction, evidenced by muricidal actions. Additionally, there was a significant increase in depression-related behavior, especially in the anhedonia test. However, all these aberrations were attenuated following PRF treatment, a result similar to what is obtained in the diazepam treatment group. Conclusively, proanthocyanidins-rich-fraction from Viti's vinifera seed attenuates the markers of psychosis following CSE in juvenile Wistar rats.

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Section: Introductionmentioning

confidence: 99%

Modulation of the Indices of Psychosis in Post-Convulsive Status Epilepticus Model: The Role of Proanthocyanidin-Rich Fraction

2022

TJNPR

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“…Some authors suggest that it should be considered an interictal psychosis, thus coded as a psychotic disorder due to epilepsy. 9 However, others argue that its relationship to a cease in epileptiform activity indicates a distinct phenomenon that should be categorized separately. 8,10,11 In a similar way, an optimal treatment strategy has not been established, currently accepting as adequate approaches: (1) reduction or discontinuation of antiepileptic medication, (2) change of antiepileptic medication, and/or (3) treatment of psychotic symptoms with second-generation antipsychotics.…”

mentioning

confidence: 99%

“…The classification of FN within the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria is controversial. Some authors suggest that it should be considered an interictal psychosis, thus coded as a psychotic disorder due to epilepsy 9 . However, others argue that its relationship to a cease in epileptiform activity indicates a distinct phenomenon that should be categorized separately 8,10,11 .…”

mentioning

confidence: 99%