Les onychomycoses � moisissures

In the 5-year period 1994-1998, 13957 patients were examined in the Mycological Laboratory of the State Hospital for Skin and Venereal Diseases, in Thessaloniki, Greece. Of the 2766 patients presenting with onychomycoses (20%), 67% were women and 33% were men. In the toenail infections, dermatophytes were most often isolated (72.3%), especially in women, followed by moulds (9.6%) and yeasts (2%); 16.1% of the infections were mixed. In the fingernail infections mostly yeasts were isolated (72%), especially in women, followed by dermatophytes (10%) and moulds (5.6%); 12.4% of the infections were mixed.

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Onychomycosis in Northern Greece during 1994–1998

Koussidou

Devliotou-Panagiotidou

Karakatsanis

et al. 2002

“…sclerotium, A. sydowi and A . versicolor among others (1,2,3,4,5,10,11,12,13).Theconfirmation of saphrophytic molds as the agents responsible of infection of nails is difficult because it is indispensable to discard a contamination. We describe a well-documented case of onychomycosis produced by Aspergillus varians (A. versicolor group), isolated from two toe-nails of the same patient, and the procedures to establish a firm diagnosis are analyzed.…”

Section: Introductionmentioning

confidence: 99%

Onychomycosis Due to a Fungus of the Aspergillus versicolor Group

Torres-Rodríguez

Balaguer-Meler

Martı́nez³

et al. 1988

Summary: A case of onychomycosis involving both big toe nails caused by a fungus of the Aspergillus versicolor group is described. The presence of hyaline hyphae and conidia in direct microscopy and the repeated isolation in culture of the fungus from the nails before and after extirpation, as well the histopathologic findings, are taken as demonstration of the fungal invasion of the nail tissue. After surgical treatment, the nails grew well and no further Aspergillus isolations were done. Zusammenfassung: Es wird ein durch einen Pilz aus der Aspergillus versicolor‐ Gruppe verursachter Fall beschrieben, der sowohl Zehen als auch Fingernägel betraf. Die Anwesenheit hyaliner Hyphen und Konidien im Nativpräparat und die wiederholte Isolierung von Pilzen der Aspergillus versicolor‐Gruppe in Pilzkulturen von den Nägeln jeweils vor und nach der Exstirpation, wie auch die histopathologischen Befunde werden als Beweis für die Pilzinvasion in das Nagelgewebe betrachtet. Nach einer chirurgischen Behandlung wuchsen die Nägel gut, und weitere Aspergillus‐Isolierungen erfolgten nicht.

“…Depuis la premiere observation decrite par Langeron et Brumpt (13) il n'est pas rare a partir de prelevements au niveau de la peau et des phaneres d'isoler Scopulariopsis brevicaulis Bainier (20, 39,47,54,55,44,15,4,48,46,45,3,8,9,10,35,34,42,14,56,25,16,22,51,33,7,65,38, 5,58,17,57,40,37,67,43,66,28,21,6,1,2,18,26,31,50,62).…”

Section: Introductionunclassified

“…A propos d'un cas d'onychomycose du gros orteil evoluant depuis plusieurs annees malgre des traitements probablement ma1 suivis, insuffisants et inadaptes, nous avons ete amenes a rechercher la sensibilite de cette espece de champignon filamenteux aux principaux antifongiques utilises en therapeutique. Le caractere rebelle de cette mycose est souligne par de nombreux cliniciens (2,6,20,28) mais la litterature foumit genkralement des indications partielles, la plupart des auteurs travaillant sur un nombre limite de souches et de principes actifs (2,6,7,11,15,17,18 (36).…”

Section: Introductionunclassified

Contribution à L'Etude de la Sensibilité de Scopulariopsis brevicaulis (Bainier) aux Antifongiques

Régli¹,

Ferrari²,

Y³

et al. 1984

Résumé: 38 souches de Scopulariopsis brevicaulis isolées de prélèvements au niveau de lésions de la peau et des phanères sont testées comparativement à 3 souches de Scopulariopsis de référence, afin d'apprécier leur sensibilité aux antifongiques utilisés dans le traitement des mycoses. Sont envisagées en utilisant les techniques de la C. M. I. (concentration minimum inhibitrice) sur trois milieux solides (Sabouraud, YMA, Casitone) les sensibilités vis‐à‐vis: ‐ des antibiotiques: Nystatine, Amphotéricine B, Pimaricine, Griséofulvine. ‐ des dérivés imidazoles: Clotrimazole, Miconazole, Econazole, Isoconazole, Kétoconazole. ‐ des antimétabolites: 5 FC ‐ du Tolnaftate. Scopulariopsis brevicaulis possède généralement une grande résistance vis‐à‐vis des antifongiques. Parmi les antibiotiques testés la Griséofulvine et l'Amphotéricine semblent inefficaces (C. M. I. sup. à 1000 γ/ml) la Nystatine possède une certaine activité (50 γ/ml) la Pimaricine étant la plus active (5 γ/ml). Parmi les produits chimiques la 5 FC et le Tolnaftate n'ont pas d'action (C. M. I. sup. à 1000 γ/ ml); par contre, les dérivés imidazoles possèdent tous une efficacité certaine vis‐à‐vis de ce champignon dont le caractère pathogène est souvent discuté. Summary: 38 strains of Scopulariopsis brevicaulis isolated from lesions of the skin and from cutaneous appandages were tested against antimycotics in comparison to 3 strains (2 S. brevicaulis, 1 S. brumptii) taken from culture collections. Minimal inhibitory concentrations were determined on different solid media using the following antifungals: nystatine, amphotericine B, pimaricine, griseofulvin, clotrimazole, miconazole, econazole, isoconazole, ketoconazole, 5‐flucytosine, tolnaftate. In general, S. brevicaulis showed remarkable resistance against the antifugal substances. Among the antibiotics, griseofulvin and amphotericin B were without effect (MIC > 1000 μg/ml). Nystatine had some inhibitory activity (MIC = 50 μg/ml) while pimaricine was the most active substance (MIC = 5 μg/ml). Among the antimycotic chemicals, flucytosine and tolnaftate were ineffective while all the imidazoles had some inhibitory activity against this fungus whose role as pathogen is often discussed.